BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors

Choroid plexus epithelial cells (CPECs) have essential developmental and homeostatic roles related to the CSF and blood-CSF barrier they produce. Accordingly, CPEC dysfunction has been implicated in many neurological disorders, such as Alzheimer's disease, and transplant studies have provided p...

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Veröffentlicht in:	The Journal of neuroscience 2012-11, Vol.32 (45), p.15934-15945
Hauptverfasser:	Watanabe, Momoko, Kang, Young-Jin, Davies, Lauren M, Meghpara, Sanket, Lau, Kimbley, Chung, Chi-Yeh, Kathiriya, Jaymin, Hadjantonakis, Anna-Katerina, Monuki, Edwin S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Protein 4 - pharmacology Cell Differentiation - drug effects Cell Line Cells, Cultured Choroid Plexus - cytology Choroid Plexus - drug effects Embryonic Stem Cells - cytology Embryonic Stem Cells - drug effects Epithelial Cells - cytology Epithelial Cells - drug effects Humans Mice Neural Stem Cells - cytology Neural Stem Cells - drug effects
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