Structure, Function, and Modulation of GABAA Receptors

The GABAA receptors are the major inhibitory neurotransmitter receptors in mammalian brain. Each isoform consists of five homologous or identical subunits surrounding a central chloride ion-selective channel gated by GABA. How many isoforms of the receptor exist is far from clear. GABAA receptors lo...

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Veröffentlicht in:	The Journal of biological chemistry 2012-11, Vol.287 (48), p.40224-40231
Hauptverfasser:	Sigel, Erwin, Steinmann, Michael E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzodiazepines Cys Loop Receptors GABA Receptors Ion Channels Membrane Proteins Minireviews Neurobiology Protein Purification
Online-Zugang:	Volltext
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