Establishment of a conditional transgenic mouse model expressing human uncoupling protein 2 in vascular smooth muscle cells

Increased oxidative stress is involved in the development of vascular dysfunction and remodeling. Uncoupling protein 2 (UCP2) regulates the production of reactive oxygen species in vascular smooth muscle cells (SMCs). To promote the study of the role of UCP2 in vascular diseases, a transgenic mouse...

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Veröffentlicht in:	Experimental and therapeutic medicine 2012-09, Vol.4 (3), p.545-547
Hauptverfasser:	MA, SHUANGTAO, LI, DE, YANG, DACHUN, TAN, YAN, TANG, BING, JIN, FEIPENG, JIANG, SIHUA, LI, XIUCHUAN, YANG, YONGJIAN
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Bioavailability Coronary vessels Gene expression Proteins Reactive oxygen species Rodents Smooth muscle Studies Transgenic animals transgenic mouse uncoupling protein 2 vascular smooth muscle cell
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