Effect of ligand density, receptor density, and nanoparticle size on cell targeting

Abstract It is generally accepted that the presentation of multiple ligands on a nanoparticle (NP) surface can improve cell targeting; however, little work has been done to determine whether an optimal ligand density exists. We have recently developed a site-specific bioconjugation strategy that all...

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Veröffentlicht in:Nanomedicine 2013-02, Vol.9 (2), p.194-201
Hauptverfasser: Elias, Drew R., BS, Poloukhtine, Andrei, PhD, Popik, Vladimir, PhD, Tsourkas, Andrew, PhD
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Sprache:eng
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