Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats

► Methodological refinement improved survival from stroke in hypertensive rats. ► Post-stroke associated weight loss is reduced in animals with pre-stroke surgery. ► Surviving animals (±pre-stroke surgery) have equivalent infarct volumes. ► Surviving animals (±pre-stroke surgery) show same neurologi...

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Veröffentlicht in:	Journal of neuroscience methods 2012-11, Vol.211 (2), p.305-308
Hauptverfasser:	Ord, Emily N.J., Shirley, Rachel, van Kralingen, Josie C., Graves, Alice, McClure, John D., Wilkinson, Michael, McCabe, Christopher, Macrae, I. Mhairi, Work, Lorraine M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Neuroscience Closed skull stroke model Cranial burrhole Disease Models, Animal Hypertension - complications Hypertensive rat Ischemic Attack, Transient - pathology Ischemic Attack, Transient - physiopathology Male Rats Rats, Inbred SHR Stroke - pathology Stroke - physiopathology Survival Transient focal ischemia Trephining
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