Neighborhood built environment and income: Examining multiple health outcomes

There is growing interest in the relation of built environments to physical activity, obesity, and other health outcomes. The purpose of the present study was to test associations of neighborhood built environment and median income to multiple health outcomes and examine whether associations are sim...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Social science & medicine (1982) 2009-04, Vol.68 (7), p.1285-1293
Hauptverfasser: Sallis, James F., Saelens, Brian E., Frank, Lawrence D., Conway, Terry L., Slymen, Donald J., Cain, Kelli L., Chapman, James E., Kerr, Jacqueline
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1293
container_issue 7
container_start_page 1285
container_title Social science & medicine (1982)
container_volume 68
creator Sallis, James F.
Saelens, Brian E.
Frank, Lawrence D.
Conway, Terry L.
Slymen, Donald J.
Cain, Kelli L.
Chapman, James E.
Kerr, Jacqueline
description There is growing interest in the relation of built environments to physical activity, obesity, and other health outcomes. The purpose of the present study was to test associations of neighborhood built environment and median income to multiple health outcomes and examine whether associations are similar for low- and high-income groups. This was a cross-sectional study of 32 neighborhoods in Seattle, WA and Baltimore, MD regions, stratified by income and walkability, and conducted between 2001 and 2005. Participants were adults aged 20–65 years ( n = 2199; 26% ethnic minority). The main outcomes were daily minutes of moderate-to-vigorous physical activity (MVPA) from accelerometer monitoring, body mass index (BMI) based on self-report, and mental and physical quality of life (QoL) assessed with the SF-12. We found that MVPA was higher in high- vs. low-walkability neighborhoods but did not differ by neighborhood income. Overweight/obesity (BMI ≥25) was lower in high-walkability neighborhoods. Physical QoL was higher in high-income neighborhoods but unrelated to walkability. Adjustment for neighborhood self-selection produced minor changes. We concluded that living in walkable neighborhoods was associated with more physical activity and lower overweight/obesity but not with other benefits. Lower- and higher-income groups benefited similarly from living in high-walkability neighborhoods. Adults in higher-income neighborhoods had lower BMI and higher physical QoL.
doi_str_mv 10.1016/j.socscimed.2009.01.017
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3500640</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0277953609000318</els_id><sourcerecordid>61377398</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-88dc498cfeab007c35cd02637564308175d690d3a5a98b8edd83a41bb0fc046a3</originalsourceid><addsrcrecordid>eNqNkk2P0zAQhiMEYrsLfwEiJLi1jO34IxxWWq12AanABc6W40wbV4ld7KRi_z0urcrHpUgz8SHPvJ68eYviJYEFASLebhYp2GTdgO2CAtQLILnko2JGlGRzzir5uJgBlXJecyYuisuUNgBAQLGnxQWpKaMK6lnx6TO6ddeE2IXQls3k-rFEv3Mx-AH9WBrfls7bMOC78u6HGZx3fl0OUz-6bY9lh6YfuzJM4x5Jz4onK9MnfH48r4pv93dfbz_Ml1_ef7y9Wc6tqOk4V6q1Va3sCk0DIC3jtgUqmOSiYqCI5K2ooWWGm1o1CttWMVORpoGVhUoYdlVcH3S3U5MtsHnTaHq9jW4w8UEH4_Tfb7zr9DrsNOMAooIs8OYoEMP3CdOoB5cs9r3xGKakhQROJeHnQSKlpOw_FAmTktXqLMgkEQIky-Crf8BNmKLPvup8YaUY5_v95AGyMaQUcXUygYDeR0Vv9Ckqeh8VDSSXzJPLw2TELdrTGCJmfg9nt4xQ-fGQ-9cky74yI3NvcxOquCa0Zrobhyz34s9f8nuNY9Qy8PoImGRNv4rGW5dOHCWMV7SuMndz4DAHaOcw6rw8eouti2hH3QZ39tt-Ak2n-wA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>230483555</pqid></control><display><type>article</type><title>Neighborhood built environment and income: Examining multiple health outcomes</title><source>MEDLINE</source><source>RePEc</source><source>Elsevier ScienceDirect Journals</source><source>Sociological Abstracts</source><creator>Sallis, James F. ; Saelens, Brian E. ; Frank, Lawrence D. ; Conway, Terry L. ; Slymen, Donald J. ; Cain, Kelli L. ; Chapman, James E. ; Kerr, Jacqueline</creator><creatorcontrib>Sallis, James F. ; Saelens, Brian E. ; Frank, Lawrence D. ; Conway, Terry L. ; Slymen, Donald J. ; Cain, Kelli L. ; Chapman, James E. ; Kerr, Jacqueline</creatorcontrib><description>There is growing interest in the relation of built environments to physical activity, obesity, and other health outcomes. The purpose of the present study was to test associations of neighborhood built environment and median income to multiple health outcomes and examine whether associations are similar for low- and high-income groups. This was a cross-sectional study of 32 neighborhoods in Seattle, WA and Baltimore, MD regions, stratified by income and walkability, and conducted between 2001 and 2005. Participants were adults aged 20–65 years ( n = 2199; 26% ethnic minority). The main outcomes were daily minutes of moderate-to-vigorous physical activity (MVPA) from accelerometer monitoring, body mass index (BMI) based on self-report, and mental and physical quality of life (QoL) assessed with the SF-12. We found that MVPA was higher in high- vs. low-walkability neighborhoods but did not differ by neighborhood income. Overweight/obesity (BMI ≥25) was lower in high-walkability neighborhoods. Physical QoL was higher in high-income neighborhoods but unrelated to walkability. Adjustment for neighborhood self-selection produced minor changes. We concluded that living in walkable neighborhoods was associated with more physical activity and lower overweight/obesity but not with other benefits. Lower- and higher-income groups benefited similarly from living in high-walkability neighborhoods. Adults in higher-income neighborhoods had lower BMI and higher physical QoL.</description><identifier>ISSN: 0277-9536</identifier><identifier>EISSN: 1873-5347</identifier><identifier>DOI: 10.1016/j.socscimed.2009.01.017</identifier><identifier>PMID: 19232809</identifier><identifier>CODEN: SSMDEP</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adult ; Baltimore ; Baltimore, Maryland ; Biological and medical sciences ; Buildings ; Built Environment ; Environment. Living conditions ; Female ; Health ; Health Behavior ; Health disparities ; Humans ; Income ; Life satisfaction ; Life Style ; Logistic Models ; Male ; Medical research ; Medical sciences ; Medical sociology ; Metabolic diseases ; Middle Aged ; Miscellaneous ; Motor Activity ; Neighborhood ; Neighborhoods ; Neighbourhoods ; Obesity ; Obesity - epidemiology ; Obesity Physical activity Built environment Health disparities USA Quality of life (QoL) Neighborhood Walkability ; Physical activity ; Physical Fitness ; Public health ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Public spaces ; Quality of Life ; Quality of life (QoL) ; Residence Characteristics - classification ; Residence Characteristics - statistics &amp; numerical data ; Seattle, Washington ; Social Inequality ; Social research ; U.S.A ; Urban Population - statistics &amp; numerical data ; USA ; Walkability ; Walking ; Washington</subject><ispartof>Social science &amp; medicine (1982), 2009-04, Vol.68 (7), p.1285-1293</ispartof><rights>2009</rights><rights>2009 INIST-CNRS</rights><rights>Copyright Pergamon Press Inc. Apr 2009</rights><rights>2012 Published by Elsevier Ltd. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-88dc498cfeab007c35cd02637564308175d690d3a5a98b8edd83a41bb0fc046a3</citedby><cites>FETCH-LOGICAL-c692t-88dc498cfeab007c35cd02637564308175d690d3a5a98b8edd83a41bb0fc046a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0277953609000318$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,3994,27901,27902,33751,33752,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=21354294$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19232809$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://econpapers.repec.org/article/eeesocmed/v_3a68_3ay_3a2009_3ai_3a7_3ap_3a1285-1293.htm$$DView record in RePEc$$Hfree_for_read</backlink></links><search><creatorcontrib>Sallis, James F.</creatorcontrib><creatorcontrib>Saelens, Brian E.</creatorcontrib><creatorcontrib>Frank, Lawrence D.</creatorcontrib><creatorcontrib>Conway, Terry L.</creatorcontrib><creatorcontrib>Slymen, Donald J.</creatorcontrib><creatorcontrib>Cain, Kelli L.</creatorcontrib><creatorcontrib>Chapman, James E.</creatorcontrib><creatorcontrib>Kerr, Jacqueline</creatorcontrib><title>Neighborhood built environment and income: Examining multiple health outcomes</title><title>Social science &amp; medicine (1982)</title><addtitle>Soc Sci Med</addtitle><description>There is growing interest in the relation of built environments to physical activity, obesity, and other health outcomes. The purpose of the present study was to test associations of neighborhood built environment and median income to multiple health outcomes and examine whether associations are similar for low- and high-income groups. This was a cross-sectional study of 32 neighborhoods in Seattle, WA and Baltimore, MD regions, stratified by income and walkability, and conducted between 2001 and 2005. Participants were adults aged 20–65 years ( n = 2199; 26% ethnic minority). The main outcomes were daily minutes of moderate-to-vigorous physical activity (MVPA) from accelerometer monitoring, body mass index (BMI) based on self-report, and mental and physical quality of life (QoL) assessed with the SF-12. We found that MVPA was higher in high- vs. low-walkability neighborhoods but did not differ by neighborhood income. Overweight/obesity (BMI ≥25) was lower in high-walkability neighborhoods. Physical QoL was higher in high-income neighborhoods but unrelated to walkability. Adjustment for neighborhood self-selection produced minor changes. We concluded that living in walkable neighborhoods was associated with more physical activity and lower overweight/obesity but not with other benefits. Lower- and higher-income groups benefited similarly from living in high-walkability neighborhoods. Adults in higher-income neighborhoods had lower BMI and higher physical QoL.</description><subject>Adult</subject><subject>Baltimore</subject><subject>Baltimore, Maryland</subject><subject>Biological and medical sciences</subject><subject>Buildings</subject><subject>Built Environment</subject><subject>Environment. Living conditions</subject><subject>Female</subject><subject>Health</subject><subject>Health Behavior</subject><subject>Health disparities</subject><subject>Humans</subject><subject>Income</subject><subject>Life satisfaction</subject><subject>Life Style</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Medical sociology</subject><subject>Metabolic diseases</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Motor Activity</subject><subject>Neighborhood</subject><subject>Neighborhoods</subject><subject>Neighbourhoods</subject><subject>Obesity</subject><subject>Obesity - epidemiology</subject><subject>Obesity Physical activity Built environment Health disparities USA Quality of life (QoL) Neighborhood Walkability</subject><subject>Physical activity</subject><subject>Physical Fitness</subject><subject>Public health</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Public spaces</subject><subject>Quality of Life</subject><subject>Quality of life (QoL)</subject><subject>Residence Characteristics - classification</subject><subject>Residence Characteristics - statistics &amp; numerical data</subject><subject>Seattle, Washington</subject><subject>Social Inequality</subject><subject>Social research</subject><subject>U.S.A</subject><subject>Urban Population - statistics &amp; numerical data</subject><subject>USA</subject><subject>Walkability</subject><subject>Walking</subject><subject>Washington</subject><issn>0277-9536</issn><issn>1873-5347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>X2L</sourceid><sourceid>BHHNA</sourceid><recordid>eNqNkk2P0zAQhiMEYrsLfwEiJLi1jO34IxxWWq12AanABc6W40wbV4ld7KRi_z0urcrHpUgz8SHPvJ68eYviJYEFASLebhYp2GTdgO2CAtQLILnko2JGlGRzzir5uJgBlXJecyYuisuUNgBAQLGnxQWpKaMK6lnx6TO6ddeE2IXQls3k-rFEv3Mx-AH9WBrfls7bMOC78u6HGZx3fl0OUz-6bY9lh6YfuzJM4x5Jz4onK9MnfH48r4pv93dfbz_Ml1_ef7y9Wc6tqOk4V6q1Va3sCk0DIC3jtgUqmOSiYqCI5K2ooWWGm1o1CttWMVORpoGVhUoYdlVcH3S3U5MtsHnTaHq9jW4w8UEH4_Tfb7zr9DrsNOMAooIs8OYoEMP3CdOoB5cs9r3xGKakhQROJeHnQSKlpOw_FAmTktXqLMgkEQIky-Crf8BNmKLPvup8YaUY5_v95AGyMaQUcXUygYDeR0Vv9Ckqeh8VDSSXzJPLw2TELdrTGCJmfg9nt4xQ-fGQ-9cky74yI3NvcxOquCa0Zrobhyz34s9f8nuNY9Qy8PoImGRNv4rGW5dOHCWMV7SuMndz4DAHaOcw6rw8eouti2hH3QZ39tt-Ak2n-wA</recordid><startdate>20090401</startdate><enddate>20090401</enddate><creator>Sallis, James F.</creator><creator>Saelens, Brian E.</creator><creator>Frank, Lawrence D.</creator><creator>Conway, Terry L.</creator><creator>Slymen, Donald J.</creator><creator>Cain, Kelli L.</creator><creator>Chapman, James E.</creator><creator>Kerr, Jacqueline</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Pergamon Press Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>DKI</scope><scope>X2L</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U3</scope><scope>7U4</scope><scope>8BJ</scope><scope>BHHNA</scope><scope>DWI</scope><scope>FQK</scope><scope>JBE</scope><scope>K9.</scope><scope>WZK</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20090401</creationdate><title>Neighborhood built environment and income: Examining multiple health outcomes</title><author>Sallis, James F. ; Saelens, Brian E. ; Frank, Lawrence D. ; Conway, Terry L. ; Slymen, Donald J. ; Cain, Kelli L. ; Chapman, James E. ; Kerr, Jacqueline</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-88dc498cfeab007c35cd02637564308175d690d3a5a98b8edd83a41bb0fc046a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Baltimore</topic><topic>Baltimore, Maryland</topic><topic>Biological and medical sciences</topic><topic>Buildings</topic><topic>Built Environment</topic><topic>Environment. Living conditions</topic><topic>Female</topic><topic>Health</topic><topic>Health Behavior</topic><topic>Health disparities</topic><topic>Humans</topic><topic>Income</topic><topic>Life satisfaction</topic><topic>Life Style</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Medical sociology</topic><topic>Metabolic diseases</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Motor Activity</topic><topic>Neighborhood</topic><topic>Neighborhoods</topic><topic>Neighbourhoods</topic><topic>Obesity</topic><topic>Obesity - epidemiology</topic><topic>Obesity Physical activity Built environment Health disparities USA Quality of life (QoL) Neighborhood Walkability</topic><topic>Physical activity</topic><topic>Physical Fitness</topic><topic>Public health</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Public spaces</topic><topic>Quality of Life</topic><topic>Quality of life (QoL)</topic><topic>Residence Characteristics - classification</topic><topic>Residence Characteristics - statistics &amp; numerical data</topic><topic>Seattle, Washington</topic><topic>Social Inequality</topic><topic>Social research</topic><topic>U.S.A</topic><topic>Urban Population - statistics &amp; numerical data</topic><topic>USA</topic><topic>Walkability</topic><topic>Walking</topic><topic>Washington</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sallis, James F.</creatorcontrib><creatorcontrib>Saelens, Brian E.</creatorcontrib><creatorcontrib>Frank, Lawrence D.</creatorcontrib><creatorcontrib>Conway, Terry L.</creatorcontrib><creatorcontrib>Slymen, Donald J.</creatorcontrib><creatorcontrib>Cain, Kelli L.</creatorcontrib><creatorcontrib>Chapman, James E.</creatorcontrib><creatorcontrib>Kerr, Jacqueline</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>RePEc IDEAS</collection><collection>RePEc</collection><collection>CrossRef</collection><collection>Social Services Abstracts</collection><collection>Sociological Abstracts (pre-2017)</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>Sociological Abstracts</collection><collection>Sociological Abstracts</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Sociological Abstracts (Ovid)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Social science &amp; medicine (1982)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sallis, James F.</au><au>Saelens, Brian E.</au><au>Frank, Lawrence D.</au><au>Conway, Terry L.</au><au>Slymen, Donald J.</au><au>Cain, Kelli L.</au><au>Chapman, James E.</au><au>Kerr, Jacqueline</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neighborhood built environment and income: Examining multiple health outcomes</atitle><jtitle>Social science &amp; medicine (1982)</jtitle><addtitle>Soc Sci Med</addtitle><date>2009-04-01</date><risdate>2009</risdate><volume>68</volume><issue>7</issue><spage>1285</spage><epage>1293</epage><pages>1285-1293</pages><issn>0277-9536</issn><eissn>1873-5347</eissn><coden>SSMDEP</coden><abstract>There is growing interest in the relation of built environments to physical activity, obesity, and other health outcomes. The purpose of the present study was to test associations of neighborhood built environment and median income to multiple health outcomes and examine whether associations are similar for low- and high-income groups. This was a cross-sectional study of 32 neighborhoods in Seattle, WA and Baltimore, MD regions, stratified by income and walkability, and conducted between 2001 and 2005. Participants were adults aged 20–65 years ( n = 2199; 26% ethnic minority). The main outcomes were daily minutes of moderate-to-vigorous physical activity (MVPA) from accelerometer monitoring, body mass index (BMI) based on self-report, and mental and physical quality of life (QoL) assessed with the SF-12. We found that MVPA was higher in high- vs. low-walkability neighborhoods but did not differ by neighborhood income. Overweight/obesity (BMI ≥25) was lower in high-walkability neighborhoods. Physical QoL was higher in high-income neighborhoods but unrelated to walkability. Adjustment for neighborhood self-selection produced minor changes. We concluded that living in walkable neighborhoods was associated with more physical activity and lower overweight/obesity but not with other benefits. Lower- and higher-income groups benefited similarly from living in high-walkability neighborhoods. Adults in higher-income neighborhoods had lower BMI and higher physical QoL.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>19232809</pmid><doi>10.1016/j.socscimed.2009.01.017</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0277-9536
ispartof Social science & medicine (1982), 2009-04, Vol.68 (7), p.1285-1293
issn 0277-9536
1873-5347
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3500640
source MEDLINE; RePEc; Elsevier ScienceDirect Journals; Sociological Abstracts
subjects Adult
Baltimore
Baltimore, Maryland
Biological and medical sciences
Buildings
Built Environment
Environment. Living conditions
Female
Health
Health Behavior
Health disparities
Humans
Income
Life satisfaction
Life Style
Logistic Models
Male
Medical research
Medical sciences
Medical sociology
Metabolic diseases
Middle Aged
Miscellaneous
Motor Activity
Neighborhood
Neighborhoods
Neighbourhoods
Obesity
Obesity - epidemiology
Obesity Physical activity Built environment Health disparities USA Quality of life (QoL) Neighborhood Walkability
Physical activity
Physical Fitness
Public health
Public health. Hygiene
Public health. Hygiene-occupational medicine
Public spaces
Quality of Life
Quality of life (QoL)
Residence Characteristics - classification
Residence Characteristics - statistics & numerical data
Seattle, Washington
Social Inequality
Social research
U.S.A
Urban Population - statistics & numerical data
USA
Walkability
Walking
Washington
title Neighborhood built environment and income: Examining multiple health outcomes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T04%3A44%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Neighborhood%20built%20environment%20and%20income:%20Examining%20multiple%20health%20outcomes&rft.jtitle=Social%20science%20&%20medicine%20(1982)&rft.au=Sallis,%20James%20F.&rft.date=2009-04-01&rft.volume=68&rft.issue=7&rft.spage=1285&rft.epage=1293&rft.pages=1285-1293&rft.issn=0277-9536&rft.eissn=1873-5347&rft.coden=SSMDEP&rft_id=info:doi/10.1016/j.socscimed.2009.01.017&rft_dat=%3Cproquest_pubme%3E61377398%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=230483555&rft_id=info:pmid/19232809&rft_els_id=S0277953609000318&rfr_iscdi=true