Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases

NOD1 {nucleotide-binding oligomerization domain 1; NLRC [NOD-LRR (leucine-rich repeat) family with CARD (caspase recruitment domain) 1]} and NOD2 (NLRC2) are among the most prominent members of the NLR (NOD-LRR) family -proteins that contain nucleotide-binding NACHT domains and receptor-like LRR dom...

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Veröffentlicht in:	Bioscience reports 2012-12, Vol.32 (6), p.597-608
Hauptverfasser:	Correa, Ricardo G, Milutinovic, Snezana, Reed, John C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Bacterial Infections - drug therapy Bacterial Infections - genetics Bacterial Infections - immunology Bacterial Physiological Phenomena Gene Expression Regulation Host-Pathogen Interactions Humans Immunity, Innate - drug effects Inflammation - drug therapy Inflammation - genetics Inflammation - immunology Nod1 Signaling Adaptor Protein - antagonists & inhibitors Nod1 Signaling Adaptor Protein - genetics Nod1 Signaling Adaptor Protein - immunology Nod2 Signaling Adaptor Protein - antagonists & inhibitors Nod2 Signaling Adaptor Protein - genetics Nod2 Signaling Adaptor Protein - immunology Review
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