Intravenous Hemostatic Nanoparticles Increase Survival Following Blunt Trauma Injury

Trauma is the leading cause of death for people ages 1–44, with blood loss comprising 60–70% of mortality in the absence of lethal CNS or cardiac injury. Immediate intervention is critical to improving chances of survival. While there are several products to control bleeding for external and compres...

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Veröffentlicht in:	Biomacromolecules 2012-11, Vol.13 (11), p.3850-3857
Hauptverfasser:	Shoffstall, Andrew J, Atkins, Kristyn T, Groynom, Rebecca E, Varley, Matthew E, Everhart, Lydia M, Lashof-Sullivan, Margaret M, Martyn-Dow, Blaine, Butler, Robert S, Ustin, Jeffrey S, Lavik, Erin B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied sciences Biological and medical sciences Blood Coagulation - drug effects Blood. Blood coagulation. Reticuloendothelial system Disease Models, Animal Exact sciences and technology Femoral Artery - injuries Forms of application and semi-finished materials Hemorrhage - therapy Hemostatic Techniques Hemostatics - administration & dosage Hemostatics - therapeutic use Liver - injuries Medical sciences Miscellaneous Nanoparticles - administration & dosage Nanoparticles - therapeutic use Pharmacology. Drug treatments Polyethylene Glycols - therapeutic use Polyglactin 910 - therapeutic use Polymer industry, paints, wood Rats Rats, Sprague-Dawley Survival Technology of polymers Wounds, Nonpenetrating - mortality Wounds, Nonpenetrating - therapy
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