Contribution of retinoblastoma LOH and the p53 Arg/Pro polymorphism to cervical cancer

Epidemiological studies indicate that infections by certain types of human papillomaviruses (HPVs) are causally linked to the development of cervical cancer. It is also known that HPV infections alone do not cause progression to cervical cancer, as additional genetic changes such as loss of distinct...

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Veröffentlicht in:	Molecular medicine reports 2012-09, Vol.6 (3), p.473-476
Hauptverfasser:	Eltahir, Huda A, Elhassan, Ahmed M, Ibrahim, Muntaser E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - pathology Adenocarcinoma - virology Alleles Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - virology Female Gene Frequency Genotype Human papillomavirus 16 - genetics Human papillomavirus 18 - genetics Humans Introns Loss of Heterozygosity Neoplasm Staging Polymorphism, Single Nucleotide Retinoblastoma Protein - genetics Retinoblastoma Protein - metabolism Risk Factors Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - virology
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