Epigenetic interplay between mouse endogenous retroviruses and host genes

BACKGROUND: Transposable elements are often the targets of repressive epigenetic modifications such as DNA methylation that, in theory, have the potential to spread toward nearby genes and induce epigenetic silencing. To better understand the role of DNA methylation in the relationship between trans...

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Veröffentlicht in:	Genome Biology 2012-10, Vol.13 (10), p.R89-R89, Article R89
Hauptverfasser:	Rebollo, Rita, Miceli-Royer, Katharine, Zhang, Ying, Farivar, Sharareh, Gagnier, Liane, Mager, Dixie L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatin Chromatin - metabolism DNA Methylation DNA, Viral DNA, Viral - genetics Endogenous Retroviruses Endogenous Retroviruses - genetics Epigenesis, Genetic Epigenetic inheritance epigenetics genes Genetic aspects Genetic research Genetic transcription genetics Life Sciences metabolism Methylation Mice Mice, Inbred C57BL Physiological aspects Promoter Regions, Genetic Retroviruses Terminal Repeat Sequences Transposons
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