PAK signaling in cancer

Transformation of a normal cell to a cancer cell is caused by mutations in genes that regulate proliferation, apoptosis, and invasion. Small GTPases such as Ras, Rho, Rac and Cdc42 orchestrate many of the signals that are required for malignant transformation. The p21-activated kinases (PAKs) are ef...

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Veröffentlicht in:	Cellular logistics 2012-04, Vol.2 (2), p.105-116
Hauptverfasser:	Ye, Diana Zi, Field, Jeffrey
Format:	Artikel
Sprache:	eng
Schlagworte:	amplification Binding Biology Bioscience Calcium Cancer CDC42 Cell Cycle Landes Organogenesis p21 activated kinase PAK protein kinase Proteins Rac Review
Online-Zugang:	Volltext
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