Peroxisome proliferator-activated receptor γ B cell-specific-deficient mice have an impaired antibody response

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily. PPARγ, a ligand-activated transcription factor, has important anti-inflammatory and antiproliferative functions, and it has been associated with diseases including diabetes, scarring, and ath...

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Veröffentlicht in:	The Journal of immunology (1950) 2012-11, Vol.189 (10), p.4740-4747
Hauptverfasser:	Ramon, Sesquile, Bancos, Simona, Thatcher, Thomas H, Murant, Thomas I, Moshkani, Safiehkhatoon, Sahler, Julie M, Bottaro, Andrea, Sime, Patricia J, Phipps, Richard P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - genetics Antibodies - immunology Antibody Formation - physiology Antibody Specificity - physiology Cell Differentiation - genetics Cell Differentiation - immunology DNA-Binding Proteins - genetics DNA-Binding Proteins - immunology Humans Mice Mice, Knockout Organ Specificity Plasma Cells - cytology Plasma Cells - immunology Positive Regulatory Domain I-Binding Factor 1 PPAR gamma - genetics PPAR gamma - immunology Proto-Oncogene Proteins c-bcl-6 Transcription Factors - genetics Transcription Factors - immunology
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