Length Distributions of Identity by Descent Reveal Fine-Scale Demographic History

Data-driven studies of identity by descent (IBD) were recently enabled by high-resolution genomic data from large cohorts and scalable algorithms for IBD detection. Yet, haplotype sharing currently represents an underutilized source of information for population-genetics research. We present analyti...

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Veröffentlicht in:	American journal of human genetics 2012-11, Vol.91 (5), p.809-822
Hauptverfasser:	PALAMARA, Pier Francesco, LENCZ, Todd, DARVASI, Ariel, PE'ER, Itsik
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance African Continental Ancestry Group - genetics Algorithms Biological and medical sciences Data processing Demographics Demography Founder Effect Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Genetics, Population genomics Haplotypes HapMap Project Heterozygote Historical account History Humans Jews - genetics Medical genetics Medical sciences Migration Models, Genetic Molecular and cellular biology Polymorphism, Single Nucleotide Population Density Population Dynamics Population genetics
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