Schmorl’s nodes
Introduction First described in 1927, a Schmorl’s node (SN) is the herniation of nucleus pulposus (NP) through the cartilaginous and bony end plate into the body of the adjacent vertebra. SNs are common findings on imaging, and although most SNs are asymptomatic, some have been shown to become painf...
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Veröffentlicht in: | European spine journal 2012-11, Vol.21 (11), p.2115-2121 |
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creator | Kyere, Kwaku A. Than, Khoi D. Wang, Anthony C. Rahman, Shayan U. Valdivia–Valdivia, Juan M. La Marca, Frank Park, Paul |
description | Introduction
First described in 1927, a Schmorl’s node (SN) is the herniation of nucleus pulposus (NP) through the cartilaginous and bony end plate into the body of the adjacent vertebra. SNs are common findings on imaging, and although most SNs are asymptomatic, some have been shown to become painful lesions. In this manuscript, we review the literature regarding the epidemiology, clinical presentation, pathogenesis, imaging, and management of SNs.
Materials and methods
Using databases from the US National Library of Medicine and the National Institutes of Health, relevant articles were identified.
Results
While several theories regarding the pathogenesis of SNs have been proposed, an axial load model appears to have the greatest supporting evidence. Symptomatic SNs are thought to be due to the inflammatory response solicited by the herniation of NP into the well-vascularized vertebral body. Management options for symptomatic SNs vary, ranging from medical management to surgical fusion.
Conclusion
SNs are common lesions that are often asymptomatic. In certain cases, SNs can cause back pain. No consensus on pathogenesis exists. There is no established treatment modality for symptomatic SNs. |
doi_str_mv | 10.1007/s00586-012-2325-9 |
format | Article |
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First described in 1927, a Schmorl’s node (SN) is the herniation of nucleus pulposus (NP) through the cartilaginous and bony end plate into the body of the adjacent vertebra. SNs are common findings on imaging, and although most SNs are asymptomatic, some have been shown to become painful lesions. In this manuscript, we review the literature regarding the epidemiology, clinical presentation, pathogenesis, imaging, and management of SNs.
Materials and methods
Using databases from the US National Library of Medicine and the National Institutes of Health, relevant articles were identified.
Results
While several theories regarding the pathogenesis of SNs have been proposed, an axial load model appears to have the greatest supporting evidence. Symptomatic SNs are thought to be due to the inflammatory response solicited by the herniation of NP into the well-vascularized vertebral body. Management options for symptomatic SNs vary, ranging from medical management to surgical fusion.
Conclusion
SNs are common lesions that are often asymptomatic. In certain cases, SNs can cause back pain. No consensus on pathogenesis exists. There is no established treatment modality for symptomatic SNs.</description><identifier>ISSN: 0940-6719</identifier><identifier>EISSN: 1432-0932</identifier><identifier>DOI: 10.1007/s00586-012-2325-9</identifier><identifier>PMID: 22544358</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Epidemiology ; Humans ; imaging ; Inflammation ; Intervertebral Disc Degeneration ; Intervertebral Disc Displacement ; Intervertebral discs ; Medicine ; Medicine & Public Health ; Neurosurgery ; Nodes ; nucleus pulposus ; Pain ; Review ; Review Article ; Spine ; Surgical Orthopedics ; Vertebrae</subject><ispartof>European spine journal, 2012-11, Vol.21 (11), p.2115-2121</ispartof><rights>Springer-Verlag 2012</rights><rights>Springer-Verlag Berlin Heidelberg 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-24330e3667f88aca2cb13313a617d2e1c4925fdc8f8ae3649b9335b415952df13</citedby><cites>FETCH-LOGICAL-c503t-24330e3667f88aca2cb13313a617d2e1c4925fdc8f8ae3649b9335b415952df13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481099/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481099/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22544358$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kyere, Kwaku A.</creatorcontrib><creatorcontrib>Than, Khoi D.</creatorcontrib><creatorcontrib>Wang, Anthony C.</creatorcontrib><creatorcontrib>Rahman, Shayan U.</creatorcontrib><creatorcontrib>Valdivia–Valdivia, Juan M.</creatorcontrib><creatorcontrib>La Marca, Frank</creatorcontrib><creatorcontrib>Park, Paul</creatorcontrib><title>Schmorl’s nodes</title><title>European spine journal</title><addtitle>Eur Spine J</addtitle><addtitle>Eur Spine J</addtitle><description>Introduction
First described in 1927, a Schmorl’s node (SN) is the herniation of nucleus pulposus (NP) through the cartilaginous and bony end plate into the body of the adjacent vertebra. SNs are common findings on imaging, and although most SNs are asymptomatic, some have been shown to become painful lesions. In this manuscript, we review the literature regarding the epidemiology, clinical presentation, pathogenesis, imaging, and management of SNs.
Materials and methods
Using databases from the US National Library of Medicine and the National Institutes of Health, relevant articles were identified.
Results
While several theories regarding the pathogenesis of SNs have been proposed, an axial load model appears to have the greatest supporting evidence. Symptomatic SNs are thought to be due to the inflammatory response solicited by the herniation of NP into the well-vascularized vertebral body. Management options for symptomatic SNs vary, ranging from medical management to surgical fusion.
Conclusion
SNs are common lesions that are often asymptomatic. In certain cases, SNs can cause back pain. No consensus on pathogenesis exists. There is no established treatment modality for symptomatic SNs.</description><subject>Epidemiology</subject><subject>Humans</subject><subject>imaging</subject><subject>Inflammation</subject><subject>Intervertebral Disc Degeneration</subject><subject>Intervertebral Disc Displacement</subject><subject>Intervertebral discs</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neurosurgery</subject><subject>Nodes</subject><subject>nucleus pulposus</subject><subject>Pain</subject><subject>Review</subject><subject>Review Article</subject><subject>Spine</subject><subject>Surgical Orthopedics</subject><subject>Vertebrae</subject><issn>0940-6719</issn><issn>1432-0932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkc9KAzEQxoMotlYPHr2I4MXL6kwm2U0ughT_geBBPYc0m7Ut292atII3X8PX80lMrYoKgqc5zG--mW8-xnYQDhGgOIoAUuUZIM84cZnpFdZFQTwDTXyVdUELyPICdYdtxDgGQKkhX2cdzqUQJFWXbd-44aQN9evzS9xr2tLHTbZW2Tr6rY_aY3dnp7f9i-zq-vyyf3KVOQk0y7ggAk95XlRKWWe5GyARks2xKLlHJzSXVelUpWzChB5oIjkQ6QTJywqpx46XutP5YOJL55tZsLWZhtHEhifT2pH52WlGQ3PfPhoSCkHrJHDwIRDah7mPMzMZRefr2ja-nUeDWKBSUhH_B4pSEorkoMf2f6Hjdh6a9Il3CmR64WI3LikX2hiDr77uRjCLbMwyG5OyMYtszGJm97vhr4nPMBLAl0BMrebeh2-r_1R9A3PzlzY</recordid><startdate>20121101</startdate><enddate>20121101</enddate><creator>Kyere, Kwaku A.</creator><creator>Than, Khoi D.</creator><creator>Wang, Anthony C.</creator><creator>Rahman, Shayan U.</creator><creator>Valdivia–Valdivia, Juan M.</creator><creator>La Marca, Frank</creator><creator>Park, Paul</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20121101</creationdate><title>Schmorl’s nodes</title><author>Kyere, Kwaku A. ; Than, Khoi D. ; Wang, Anthony C. ; Rahman, Shayan U. ; Valdivia–Valdivia, Juan M. ; La Marca, Frank ; Park, Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-24330e3667f88aca2cb13313a617d2e1c4925fdc8f8ae3649b9335b415952df13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Epidemiology</topic><topic>Humans</topic><topic>imaging</topic><topic>Inflammation</topic><topic>Intervertebral Disc Degeneration</topic><topic>Intervertebral Disc Displacement</topic><topic>Intervertebral discs</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neurosurgery</topic><topic>Nodes</topic><topic>nucleus pulposus</topic><topic>Pain</topic><topic>Review</topic><topic>Review Article</topic><topic>Spine</topic><topic>Surgical Orthopedics</topic><topic>Vertebrae</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kyere, Kwaku A.</creatorcontrib><creatorcontrib>Than, Khoi D.</creatorcontrib><creatorcontrib>Wang, Anthony C.</creatorcontrib><creatorcontrib>Rahman, Shayan U.</creatorcontrib><creatorcontrib>Valdivia–Valdivia, Juan M.</creatorcontrib><creatorcontrib>La Marca, Frank</creatorcontrib><creatorcontrib>Park, Paul</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European spine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kyere, Kwaku A.</au><au>Than, Khoi D.</au><au>Wang, Anthony C.</au><au>Rahman, Shayan U.</au><au>Valdivia–Valdivia, Juan M.</au><au>La Marca, Frank</au><au>Park, Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Schmorl’s nodes</atitle><jtitle>European spine journal</jtitle><stitle>Eur Spine J</stitle><addtitle>Eur Spine J</addtitle><date>2012-11-01</date><risdate>2012</risdate><volume>21</volume><issue>11</issue><spage>2115</spage><epage>2121</epage><pages>2115-2121</pages><issn>0940-6719</issn><eissn>1432-0932</eissn><abstract>Introduction
First described in 1927, a Schmorl’s node (SN) is the herniation of nucleus pulposus (NP) through the cartilaginous and bony end plate into the body of the adjacent vertebra. SNs are common findings on imaging, and although most SNs are asymptomatic, some have been shown to become painful lesions. In this manuscript, we review the literature regarding the epidemiology, clinical presentation, pathogenesis, imaging, and management of SNs.
Materials and methods
Using databases from the US National Library of Medicine and the National Institutes of Health, relevant articles were identified.
Results
While several theories regarding the pathogenesis of SNs have been proposed, an axial load model appears to have the greatest supporting evidence. Symptomatic SNs are thought to be due to the inflammatory response solicited by the herniation of NP into the well-vascularized vertebral body. Management options for symptomatic SNs vary, ranging from medical management to surgical fusion.
Conclusion
SNs are common lesions that are often asymptomatic. In certain cases, SNs can cause back pain. No consensus on pathogenesis exists. There is no established treatment modality for symptomatic SNs.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22544358</pmid><doi>10.1007/s00586-012-2325-9</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Epidemiology Humans imaging Inflammation Intervertebral Disc Degeneration Intervertebral Disc Displacement Intervertebral discs Medicine Medicine & Public Health Neurosurgery Nodes nucleus pulposus Pain Review Review Article Spine Surgical Orthopedics Vertebrae |
title | Schmorl’s nodes |
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