Modic type I changes and recovery of back pain after lumbar microdiscectomy
Purpose To investigate whether the presence of Modic changes type I (MC I) found on preoperative MRI scans represent a risk factor for persistent back pain 12 months after surgery amongst patients operated for lumbar disc herniation. Methods Cohort study of 178 consecutive patients operated with lum...
Gespeichert in:
| Veröffentlicht in: | European spine journal 2012-11, Vol.21 (11), p.2252-2258 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2258 |
|---|---|
| container_issue | 11 |
| container_start_page | 2252 |
| container_title | European spine journal |
| container_volume | 21 |
| creator | Sørlie, Andreas Moholdt, Viggo Kvistad, Kjell Arne Nygaard, Øystein P. Ingebrigtsen, Tor Iversen, Trond Kloster, Roar Solberg, Tore K. |
| description | Purpose
To investigate whether the presence of Modic changes type I (MC I) found on preoperative MRI scans represent a risk factor for persistent back pain 12 months after surgery amongst patients operated for lumbar disc herniation.
Methods
Cohort study of 178 consecutive patients operated with lumbar microdiscectomy. Preoperative MRI scans were evaluated by two independent neuroradiologists. Primary outcome measure was the visual analogue scale (VAS) for back pain. Secondary outcome measures were; VAS for leg pain, physical function (Oswestry Disability Index), and health-related quality of life (EQ-5D), self-reported benefit of the operation and employment status. The presence of MC I was used as exposition variable and adjusted for other risk factors in multivariate analyses.
Results
The Modic classification showed a high inter-observer reproducibility. Patients with MC I had less improvement of back pain 12 months after surgery, compared to those who had no or other types of MC, but this negative association no longer showed statistical significance when adjusted for smoking, which remained the only independent risk factor for persistent back pain.
Conclusions
Patients with preoperative MC I can expect less but still significant improvement of back pain 1 year after microdiscectomy, but not if they smoke cigarettes. |
| doi_str_mv | 10.1007/s00586-012-2419-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3481096</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1115529954</sourcerecordid><originalsourceid>FETCH-LOGICAL-c503t-1954c5c23e1afabfe0bfe33829c0ebe691929d9bb81d8b30ac0295082a9898e43</originalsourceid><addsrcrecordid>eNqNkU1v1DAQhi0EokvhB3BBlrhwCcz4I_FckFBVSkURFzhbjuO0KUm82Eml_fd4u6UqSEgcLB_mmdeeeRh7ifAWAZp3GUCbugIUlVBIlXrENqikqICkeMw2QAqqukE6Ys9yvgZATVA_ZUdCGCWoMRv2-UvsBs-X3Tbwc-6v3HwZMndzx1Pw8SakHY89b53_wbdumLnrl5D4uE6tS3wafCrt2Qe_xGn3nD3p3ZjDi7v7mH3_ePrt5FN18fXs_OTDReU1yKVC0sprL2RA17u2D1COlEaQh9CGmpAEddS2BjvTSnAeBGkwwpEhE5Q8Zu8Pudu1nULnw7wkN9ptGiaXdja6wf5ZmYcrexlvrFQGgeoS8OYuIMWfa8iLnfZDjKObQ1yzRWzQmEah_A8UtRZURiro67_Q67imuWzilgKtTQOFwgNVVpdzCv39vxHs3qo9WLXFqt1btfvkVw8Hvu_4rbEA4gDkUioG04On_5n6CxfFrJU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1115055870</pqid></control><display><type>article</type><title>Modic type I changes and recovery of back pain after lumbar microdiscectomy</title><source>MEDLINE</source><source>SpringerLink Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Sørlie, Andreas ; Moholdt, Viggo ; Kvistad, Kjell Arne ; Nygaard, Øystein P. ; Ingebrigtsen, Tor ; Iversen, Trond ; Kloster, Roar ; Solberg, Tore K.</creator><creatorcontrib>Sørlie, Andreas ; Moholdt, Viggo ; Kvistad, Kjell Arne ; Nygaard, Øystein P. ; Ingebrigtsen, Tor ; Iversen, Trond ; Kloster, Roar ; Solberg, Tore K.</creatorcontrib><description>Purpose
To investigate whether the presence of Modic changes type I (MC I) found on preoperative MRI scans represent a risk factor for persistent back pain 12 months after surgery amongst patients operated for lumbar disc herniation.
Methods
Cohort study of 178 consecutive patients operated with lumbar microdiscectomy. Preoperative MRI scans were evaluated by two independent neuroradiologists. Primary outcome measure was the visual analogue scale (VAS) for back pain. Secondary outcome measures were; VAS for leg pain, physical function (Oswestry Disability Index), and health-related quality of life (EQ-5D), self-reported benefit of the operation and employment status. The presence of MC I was used as exposition variable and adjusted for other risk factors in multivariate analyses.
Results
The Modic classification showed a high inter-observer reproducibility. Patients with MC I had less improvement of back pain 12 months after surgery, compared to those who had no or other types of MC, but this negative association no longer showed statistical significance when adjusted for smoking, which remained the only independent risk factor for persistent back pain.
Conclusions
Patients with preoperative MC I can expect less but still significant improvement of back pain 1 year after microdiscectomy, but not if they smoke cigarettes.</description><identifier>ISSN: 0940-6719</identifier><identifier>EISSN: 1432-0932</identifier><identifier>DOI: 10.1007/s00586-012-2419-4</identifier><identifier>PMID: 22842978</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adult ; Back Pain - etiology ; Back Pain - surgery ; Bone surgery ; Cigarettes ; Classification ; Diskectomy - methods ; Female ; Humans ; Intervertebral Disc Displacement - pathology ; Intervertebral Disc Displacement - surgery ; Intervertebral discs ; Leg ; Lumbar Vertebrae ; Magnetic Resonance Imaging ; Male ; Medicine ; Medicine & Public Health ; Microsurgery ; Multivariate analysis ; Neurosurgery ; Original ; Original Article ; Pain ; Pain Measurement ; Quality of life ; Risk factors ; Smoke ; Smoking ; Smoking - adverse effects ; Spine (lumbar) ; Statistics ; Surgery ; Surgical Orthopedics ; Treatment Outcome</subject><ispartof>European spine journal, 2012-11, Vol.21 (11), p.2252-2258</ispartof><rights>Springer-Verlag 2012</rights><rights>Springer-Verlag Berlin Heidelberg 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-1954c5c23e1afabfe0bfe33829c0ebe691929d9bb81d8b30ac0295082a9898e43</citedby><cites>FETCH-LOGICAL-c503t-1954c5c23e1afabfe0bfe33829c0ebe691929d9bb81d8b30ac0295082a9898e43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481096/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481096/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22842978$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sørlie, Andreas</creatorcontrib><creatorcontrib>Moholdt, Viggo</creatorcontrib><creatorcontrib>Kvistad, Kjell Arne</creatorcontrib><creatorcontrib>Nygaard, Øystein P.</creatorcontrib><creatorcontrib>Ingebrigtsen, Tor</creatorcontrib><creatorcontrib>Iversen, Trond</creatorcontrib><creatorcontrib>Kloster, Roar</creatorcontrib><creatorcontrib>Solberg, Tore K.</creatorcontrib><title>Modic type I changes and recovery of back pain after lumbar microdiscectomy</title><title>European spine journal</title><addtitle>Eur Spine J</addtitle><addtitle>Eur Spine J</addtitle><description>Purpose
To investigate whether the presence of Modic changes type I (MC I) found on preoperative MRI scans represent a risk factor for persistent back pain 12 months after surgery amongst patients operated for lumbar disc herniation.
Methods
Cohort study of 178 consecutive patients operated with lumbar microdiscectomy. Preoperative MRI scans were evaluated by two independent neuroradiologists. Primary outcome measure was the visual analogue scale (VAS) for back pain. Secondary outcome measures were; VAS for leg pain, physical function (Oswestry Disability Index), and health-related quality of life (EQ-5D), self-reported benefit of the operation and employment status. The presence of MC I was used as exposition variable and adjusted for other risk factors in multivariate analyses.
Results
The Modic classification showed a high inter-observer reproducibility. Patients with MC I had less improvement of back pain 12 months after surgery, compared to those who had no or other types of MC, but this negative association no longer showed statistical significance when adjusted for smoking, which remained the only independent risk factor for persistent back pain.
Conclusions
Patients with preoperative MC I can expect less but still significant improvement of back pain 1 year after microdiscectomy, but not if they smoke cigarettes.</description><subject>Adult</subject><subject>Back Pain - etiology</subject><subject>Back Pain - surgery</subject><subject>Bone surgery</subject><subject>Cigarettes</subject><subject>Classification</subject><subject>Diskectomy - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Intervertebral Disc Displacement - pathology</subject><subject>Intervertebral Disc Displacement - surgery</subject><subject>Intervertebral discs</subject><subject>Leg</subject><subject>Lumbar Vertebrae</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Microsurgery</subject><subject>Multivariate analysis</subject><subject>Neurosurgery</subject><subject>Original</subject><subject>Original Article</subject><subject>Pain</subject><subject>Pain Measurement</subject><subject>Quality of life</subject><subject>Risk factors</subject><subject>Smoke</subject><subject>Smoking</subject><subject>Smoking - adverse effects</subject><subject>Spine (lumbar)</subject><subject>Statistics</subject><subject>Surgery</subject><subject>Surgical Orthopedics</subject><subject>Treatment Outcome</subject><issn>0940-6719</issn><issn>1432-0932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkU1v1DAQhi0EokvhB3BBlrhwCcz4I_FckFBVSkURFzhbjuO0KUm82Eml_fd4u6UqSEgcLB_mmdeeeRh7ifAWAZp3GUCbugIUlVBIlXrENqikqICkeMw2QAqqukE6Ys9yvgZATVA_ZUdCGCWoMRv2-UvsBs-X3Tbwc-6v3HwZMndzx1Pw8SakHY89b53_wbdumLnrl5D4uE6tS3wafCrt2Qe_xGn3nD3p3ZjDi7v7mH3_ePrt5FN18fXs_OTDReU1yKVC0sprL2RA17u2D1COlEaQh9CGmpAEddS2BjvTSnAeBGkwwpEhE5Q8Zu8Pudu1nULnw7wkN9ptGiaXdja6wf5ZmYcrexlvrFQGgeoS8OYuIMWfa8iLnfZDjKObQ1yzRWzQmEah_A8UtRZURiro67_Q67imuWzilgKtTQOFwgNVVpdzCv39vxHs3qo9WLXFqt1btfvkVw8Hvu_4rbEA4gDkUioG04On_5n6CxfFrJU</recordid><startdate>20121101</startdate><enddate>20121101</enddate><creator>Sørlie, Andreas</creator><creator>Moholdt, Viggo</creator><creator>Kvistad, Kjell Arne</creator><creator>Nygaard, Øystein P.</creator><creator>Ingebrigtsen, Tor</creator><creator>Iversen, Trond</creator><creator>Kloster, Roar</creator><creator>Solberg, Tore K.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20121101</creationdate><title>Modic type I changes and recovery of back pain after lumbar microdiscectomy</title><author>Sørlie, Andreas ; Moholdt, Viggo ; Kvistad, Kjell Arne ; Nygaard, Øystein P. ; Ingebrigtsen, Tor ; Iversen, Trond ; Kloster, Roar ; Solberg, Tore K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-1954c5c23e1afabfe0bfe33829c0ebe691929d9bb81d8b30ac0295082a9898e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Back Pain - etiology</topic><topic>Back Pain - surgery</topic><topic>Bone surgery</topic><topic>Cigarettes</topic><topic>Classification</topic><topic>Diskectomy - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Intervertebral Disc Displacement - pathology</topic><topic>Intervertebral Disc Displacement - surgery</topic><topic>Intervertebral discs</topic><topic>Leg</topic><topic>Lumbar Vertebrae</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Microsurgery</topic><topic>Multivariate analysis</topic><topic>Neurosurgery</topic><topic>Original</topic><topic>Original Article</topic><topic>Pain</topic><topic>Pain Measurement</topic><topic>Quality of life</topic><topic>Risk factors</topic><topic>Smoke</topic><topic>Smoking</topic><topic>Smoking - adverse effects</topic><topic>Spine (lumbar)</topic><topic>Statistics</topic><topic>Surgery</topic><topic>Surgical Orthopedics</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sørlie, Andreas</creatorcontrib><creatorcontrib>Moholdt, Viggo</creatorcontrib><creatorcontrib>Kvistad, Kjell Arne</creatorcontrib><creatorcontrib>Nygaard, Øystein P.</creatorcontrib><creatorcontrib>Ingebrigtsen, Tor</creatorcontrib><creatorcontrib>Iversen, Trond</creatorcontrib><creatorcontrib>Kloster, Roar</creatorcontrib><creatorcontrib>Solberg, Tore K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European spine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sørlie, Andreas</au><au>Moholdt, Viggo</au><au>Kvistad, Kjell Arne</au><au>Nygaard, Øystein P.</au><au>Ingebrigtsen, Tor</au><au>Iversen, Trond</au><au>Kloster, Roar</au><au>Solberg, Tore K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modic type I changes and recovery of back pain after lumbar microdiscectomy</atitle><jtitle>European spine journal</jtitle><stitle>Eur Spine J</stitle><addtitle>Eur Spine J</addtitle><date>2012-11-01</date><risdate>2012</risdate><volume>21</volume><issue>11</issue><spage>2252</spage><epage>2258</epage><pages>2252-2258</pages><issn>0940-6719</issn><eissn>1432-0932</eissn><abstract>Purpose
To investigate whether the presence of Modic changes type I (MC I) found on preoperative MRI scans represent a risk factor for persistent back pain 12 months after surgery amongst patients operated for lumbar disc herniation.
Methods
Cohort study of 178 consecutive patients operated with lumbar microdiscectomy. Preoperative MRI scans were evaluated by two independent neuroradiologists. Primary outcome measure was the visual analogue scale (VAS) for back pain. Secondary outcome measures were; VAS for leg pain, physical function (Oswestry Disability Index), and health-related quality of life (EQ-5D), self-reported benefit of the operation and employment status. The presence of MC I was used as exposition variable and adjusted for other risk factors in multivariate analyses.
Results
The Modic classification showed a high inter-observer reproducibility. Patients with MC I had less improvement of back pain 12 months after surgery, compared to those who had no or other types of MC, but this negative association no longer showed statistical significance when adjusted for smoking, which remained the only independent risk factor for persistent back pain.
Conclusions
Patients with preoperative MC I can expect less but still significant improvement of back pain 1 year after microdiscectomy, but not if they smoke cigarettes.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22842978</pmid><doi>10.1007/s00586-012-2419-4</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0940-6719 |
| ispartof | European spine journal, 2012-11, Vol.21 (11), p.2252-2258 |
| issn | 0940-6719 1432-0932 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3481096 |
| source | MEDLINE; SpringerLink Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult Back Pain - etiology Back Pain - surgery Bone surgery Cigarettes Classification Diskectomy - methods Female Humans Intervertebral Disc Displacement - pathology Intervertebral Disc Displacement - surgery Intervertebral discs Leg Lumbar Vertebrae Magnetic Resonance Imaging Male Medicine Medicine & Public Health Microsurgery Multivariate analysis Neurosurgery Original Original Article Pain Pain Measurement Quality of life Risk factors Smoke Smoking Smoking - adverse effects Spine (lumbar) Statistics Surgery Surgical Orthopedics Treatment Outcome |
| title | Modic type I changes and recovery of back pain after lumbar microdiscectomy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T05%3A26%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Modic%20type%20I%20changes%20and%20recovery%20of%20back%20pain%20after%20lumbar%20microdiscectomy&rft.jtitle=European%20spine%20journal&rft.au=S%C3%B8rlie,%20Andreas&rft.date=2012-11-01&rft.volume=21&rft.issue=11&rft.spage=2252&rft.epage=2258&rft.pages=2252-2258&rft.issn=0940-6719&rft.eissn=1432-0932&rft_id=info:doi/10.1007/s00586-012-2419-4&rft_dat=%3Cproquest_pubme%3E1115529954%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1115055870&rft_id=info:pmid/22842978&rfr_iscdi=true |