Diurnal Pattern to Insulin Secretion and Insulin Action in Healthy Individuals

Evaluation of the existence of a diurnal pattern of glucose tolerance after mixed meals is important to inform a closed-loop system of treatment for insulin requiring diabetes. We studied 20 healthy volunteers with normal fasting glucose (4.8 ± 0.1 mmol/L) and HbA(1c) (5.2 ± 0.0%) to determine such...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2012-11, Vol.61 (11), p.2691-2700
Hauptverfasser:	SAAD, Ahmed, MAN, Chiara Dalla, BASU, Ananda, NANDY, Debashis K, LEVINE, James A, BHARUCHA, Adil E, RIZZA, Robert A, BASU, Rita, CARTER, Rickey E, COBELLI, Claudio, KUDVA, Yogish C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analysis Biological and medical sciences Blood glucose Blood Glucose - analysis Blood sugar Calories Carbohydrates Carbon Isotopes Circadian Rhythm Circadian rhythms Cohort Studies Cross-Over Studies Deuterium Diabetes Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Exercise Female Gluconeogenesis Glucose Glucose - metabolism Glucose Intolerance - blood Glucose Intolerance - metabolism Hormone replacement therapy Humans Insulin Insulin - blood Insulin - metabolism Insulin Resistance Insulin Secretion Insulin-Secreting Cells - metabolism Latin square design Male Meals Medical sciences Metabolism Middle Aged Postprandial Period Young Adult
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