Stoichiometry of the human glycine receptor revealed by direct subunit counting

The subunit stoichiometry of heteromeric glycine-gated channels determines fundamental properties of these key inhibitory neurotransmitter receptors; however, the ratio of α1- to β-subunits per receptor remains controversial. We used single-molecule imaging and stepwise photobleaching in Xenopus ooc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of neuroscience 2012-09, Vol.32 (37), p.12915-12920
Hauptverfasser:	Durisic, Nela, Godin, Antoine G, Wever, Claudia M, Heyes, Colin D, Lakadamyali, Melike, Dent, Joseph A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brief Communications Cells, Cultured Female Humans Oocytes - chemistry Oocytes - metabolism Protein Subunits - analysis Receptors, Glycine - chemistry Receptors, Glycine - classification Receptors, Glycine - metabolism Xenopus laevis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!