Anti-VEGF therapies in the clinic

The development and use of antiangiogenesis agents, particularly those targeting vascular endothelial growth factor (VEGF), has become an integral component of anticancer regimens for many tumor types. This review is intended to highlight some of the most important clinical successes and failures of...

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Veröffentlicht in:	Cold Spring Harbor perspectives in medicine 2012-10, Vol.2 (10), p.a006577-a006577
Hauptverfasser:	Meadows, Kellen L, Hurwitz, Herbert I
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - adverse effects Angiogenesis Inhibitors - therapeutic use Biomarkers, Tumor - metabolism Drug Approval Humans Neoplasms - blood supply Neoplasms - drug therapy Neoplasms - pathology Neovascularization, Pathologic - drug therapy Treatment Outcome Vascular Endothelial Growth Factor A - antagonists & inhibitors
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