Asymmetric Synthesis of Trifluoromethylated Amines via Catalytic Enantioselective Isomerization of Imines

A new approach toward the asymmetric synthesis of optically active trifluoromethylated amines was enabled by an unprecedented, highly enantioselective catalytic isomerization of trifluoromethyl imines with a new chiral organic catalyst. Not only aryl but also alkyl trifluoromethylated amines could b...

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Veröffentlicht in:	Journal of the American Chemical Society 2012-09, Vol.134 (35), p.14334-14337
Hauptverfasser:	Wu, Yongwei, Deng, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	amines Amines - chemical synthesis Amines - chemistry Catalysis catalysts Chemistry Techniques, Synthetic Chlorofluorocarbons, Methane - chemistry enantiomers Imines - chemistry isomerization Stereoisomerism Substrate Specificity
Online-Zugang:	Volltext
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