Prescription Patterns of Chinese Herbal Products for Osteoporosis in Taiwan: A Population-Based Study
Traditional Chinese medicine (TCM) includes Chinese herbal products (CHPs), acupuncture, and traumatology manipulative therapies. TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used and their patterns of prescriptions have yet to be characterized. This stu...
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description | Traditional Chinese medicine (TCM) includes Chinese herbal products (CHPs), acupuncture, and traumatology manipulative therapies. TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used and their patterns of prescriptions have yet to be characterized. This study, therefore, aimed to evaluate the CHP used for the treatment of osteoporosis in Taiwan and their prescription patterns. Methods. A cohort of one million randomly sampled cases from the National Health Insurance Research Database (NHIRD) was analyzed to evaluate the frequencies and percentages of herbal formula and single herb prescriptions for osteoporosis. Association rules were then applied to evaluate the CHP coprescription patterns and the prevalence of osteoporosis. Results. The osteoporosis cohort included 16 544 patients, of whom more than 70% had used TCM on one or more occasion. Of these patients, 4 292 (25.9%) had been hospitalized at least once because of fracture. Du-Huo-Ji-Sheng-Tang and Du Zhong (Cortex Eucommiae) were the most frequently prescribed herbal formula and single herb, respectively, for the treatment of osteoporosis. Conclusion. This study identified patterns of CHP use for the treatment of osteoporosis. However, further research is required to fully elucidate the efficacy and safety of these CHP. |
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TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used and their patterns of prescriptions have yet to be characterized. This study, therefore, aimed to evaluate the CHP used for the treatment of osteoporosis in Taiwan and their prescription patterns. Methods. A cohort of one million randomly sampled cases from the National Health Insurance Research Database (NHIRD) was analyzed to evaluate the frequencies and percentages of herbal formula and single herb prescriptions for osteoporosis. Association rules were then applied to evaluate the CHP coprescription patterns and the prevalence of osteoporosis. Results. The osteoporosis cohort included 16 544 patients, of whom more than 70% had used TCM on one or more occasion. Of these patients, 4 292 (25.9%) had been hospitalized at least once because of fracture. Du-Huo-Ji-Sheng-Tang and Du Zhong (Cortex Eucommiae) were the most frequently prescribed herbal formula and single herb, respectively, for the treatment of osteoporosis. Conclusion. This study identified patterns of CHP use for the treatment of osteoporosis. However, further research is required to fully elucidate the efficacy and safety of these CHP.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2012/752837</identifier><identifier>PMID: 23093986</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Acupuncture ; Chinese medicine ; Fractures ; Health insurance ; Herbal medicine ; Herbs ; Integrative medicine ; Medical personnel ; Medical records ; Osteoporosis ; Patients ; Pharmacy ; Physicians ; Population studies ; Population-based studies ; Prescription drugs ; Product safety ; Sexes ; Substance abuse treatment ; Traditional Chinese medicine ; Womens health</subject><ispartof>Evidence-based complementary and alternative medicine, 2012-01, Vol.2012 (2012), p.1-6</ispartof><rights>Copyright © 2012 Wei-Tai Shih et al.</rights><rights>Copyright © 2012 Wei-Tai Shih et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2012 Wei-Tai Shih et al. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c565t-40e3fe1ed8dd84cd863c449263ef79b93ebbee468245ebff70af52ed523dcf7e3</citedby><cites>FETCH-LOGICAL-c565t-40e3fe1ed8dd84cd863c449263ef79b93ebbee468245ebff70af52ed523dcf7e3</cites><orcidid>0000-0002-6242-5974</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474988/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474988/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23093986$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Soelaiman, Ima Nirwana</contributor><contributor>Ima Nirwana Soelaiman</contributor><creatorcontrib>Shih, Wei-Tai</creatorcontrib><creatorcontrib>Chen, Pau-Chung</creatorcontrib><creatorcontrib>Yang, Yao-Hsu</creatorcontrib><title>Prescription Patterns of Chinese Herbal Products for Osteoporosis in Taiwan: A Population-Based Study</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>Traditional Chinese medicine (TCM) includes Chinese herbal products (CHPs), acupuncture, and traumatology manipulative therapies. TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used and their patterns of prescriptions have yet to be characterized. This study, therefore, aimed to evaluate the CHP used for the treatment of osteoporosis in Taiwan and their prescription patterns. Methods. A cohort of one million randomly sampled cases from the National Health Insurance Research Database (NHIRD) was analyzed to evaluate the frequencies and percentages of herbal formula and single herb prescriptions for osteoporosis. Association rules were then applied to evaluate the CHP coprescription patterns and the prevalence of osteoporosis. Results. The osteoporosis cohort included 16 544 patients, of whom more than 70% had used TCM on one or more occasion. Of these patients, 4 292 (25.9%) had been hospitalized at least once because of fracture. Du-Huo-Ji-Sheng-Tang and Du Zhong (Cortex Eucommiae) were the most frequently prescribed herbal formula and single herb, respectively, for the treatment of osteoporosis. Conclusion. This study identified patterns of CHP use for the treatment of osteoporosis. However, further research is required to fully elucidate the efficacy and safety of these CHP.</description><subject>Acupuncture</subject><subject>Chinese medicine</subject><subject>Fractures</subject><subject>Health insurance</subject><subject>Herbal medicine</subject><subject>Herbs</subject><subject>Integrative medicine</subject><subject>Medical personnel</subject><subject>Medical records</subject><subject>Osteoporosis</subject><subject>Patients</subject><subject>Pharmacy</subject><subject>Physicians</subject><subject>Population studies</subject><subject>Population-based studies</subject><subject>Prescription drugs</subject><subject>Product safety</subject><subject>Sexes</subject><subject>Substance abuse treatment</subject><subject>Traditional Chinese medicine</subject><subject>Womens health</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0U1rFTEUBuBBLLZWV66VgBuxjM3nJONCqBdrhUIvWMFdyCQnNmXuZJrMWPrvzWXai7rRVQ7k4SU5b1W9IPgdIUIcU0zosRRUMfmoOiCSk5pTpR7vZvl9v3qa8zXGtJVSPqn2KcMta1VzUME6QbYpjFOIA1qbaYI0ZBQ9Wl2FATKgM0id6dE6RTfbKSMfE7rIE8QxpphDRmFAlybcmuE9OkHrOM692YbVH00Gh75Os7t7Vu1502d4fn8eVt9OP12uzurzi89fVifntRWNmGqOgXkg4JRzilunGmY5b2nDwMu2axl0HQBvFOUCOu8lNl5QcIIyZ70Edlh9WHLHuduAszBMyfR6TGFj0p2OJug_b4ZwpX_En5pxyVulSsCb-4AUb2bIk96EbKHvzQBxzprIRgmJCf8PWsrBDReEF_r6L3od5zSUTWiKG6owlgoXdbQoW_aaE_jduwnW26b1tmm9NF30q9-_urMP1RbwdgGlR2duwz_SXi4YCgFvdrgt2yeS_QL48rt_</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Shih, Wei-Tai</creator><creator>Chen, Pau-Chung</creator><creator>Yang, Yao-Hsu</creator><general>Hindawi Publishing Corporation</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QP</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6242-5974</orcidid></search><sort><creationdate>20120101</creationdate><title>Prescription Patterns of Chinese Herbal Products for Osteoporosis in Taiwan: A Population-Based Study</title><author>Shih, Wei-Tai ; 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TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used and their patterns of prescriptions have yet to be characterized. This study, therefore, aimed to evaluate the CHP used for the treatment of osteoporosis in Taiwan and their prescription patterns. Methods. A cohort of one million randomly sampled cases from the National Health Insurance Research Database (NHIRD) was analyzed to evaluate the frequencies and percentages of herbal formula and single herb prescriptions for osteoporosis. Association rules were then applied to evaluate the CHP coprescription patterns and the prevalence of osteoporosis. Results. The osteoporosis cohort included 16 544 patients, of whom more than 70% had used TCM on one or more occasion. Of these patients, 4 292 (25.9%) had been hospitalized at least once because of fracture. Du-Huo-Ji-Sheng-Tang and Du Zhong (Cortex Eucommiae) were the most frequently prescribed herbal formula and single herb, respectively, for the treatment of osteoporosis. Conclusion. This study identified patterns of CHP use for the treatment of osteoporosis. However, further research is required to fully elucidate the efficacy and safety of these CHP.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>23093986</pmid><doi>10.1155/2012/752837</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-6242-5974</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Acupuncture Chinese medicine Fractures Health insurance Herbal medicine Herbs Integrative medicine Medical personnel Medical records Osteoporosis Patients Pharmacy Physicians Population studies Population-based studies Prescription drugs Product safety Sexes Substance abuse treatment Traditional Chinese medicine Womens health |
title | Prescription Patterns of Chinese Herbal Products for Osteoporosis in Taiwan: A Population-Based Study |
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