Taxol-Induced Anaphase Reversal: Evidence That Elongating Microtubules Can Exert a Pushing Force in Living Cells

The effects of taxol on mitosis in Haemanthus endosperm were studied. Immuno-gold staining was used to visualize microtubules; observations on microtubule arrangements were correlated with studies in vivo. Mitosis is slowed down, but not arrested, by taxol over a wide range of concentrations. Taxol...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1982-11, Vol.79 (21), p.6569-6573
Hauptverfasser:	Bajer, Andrew S., Cypher, Christopher, Molè-Bajer, Jadwiga, Howard, Harrison M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Anaphase Anaphase - drug effects Antibodies Cells Chromosomes Chromosomes - physiology Endosperm Kinetochores Metaphase Microtubules Microtubules - drug effects Microtubules - physiology Mitosis Mitosis - drug effects Motion Pictures Paclitaxel Plants Polar regions
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