The UDP-sugar-sensing P2Y14 receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils

The G i -coupled P2Y 14 receptor (P2Y 14 -R) is potently activated by UDP-sugars and UDP. Although P2Y 14 -R mRNA is prominently expressed in circulating neutrophils, the signaling pathways and functional responses associated with this receptor are undefined. In this study, we illustrate that incuba...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2012-09, Vol.303 (5), p.C490-C498
Hauptverfasser:	Sesma, Juliana I., Kreda, Silvia M., Steinckwich-Besancon, Natacha, Dang, Hong, García-Mata, Rafael, Harden, T. Kendall, Lazarowski, Eduardo R.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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