Dental caries and first permanent molar pit and fissure morphology in 7- to 8-year-old children in Wuhan, China

To obtain the caries experience and, plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan, as a reasonable prediction of caries risk and preventive attention in the future, a convenient sample of five primary schools in the vicinity of the Wu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of oral science 2012-09, Vol.4 (3), p.157-160
Hauptverfasser: Wang, Jin-Dong, Chen, Xi, Frencken, Jo, Du, Min-Quan, Chen, Zhi
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 160
container_issue 3
container_start_page 157
container_title International journal of oral science
container_volume 4
creator Wang, Jin-Dong
Chen, Xi
Frencken, Jo
Du, Min-Quan
Chen, Zhi
description To obtain the caries experience and, plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan, as a reasonable prediction of caries risk and preventive attention in the future, a convenient sample of five primary schools in the vicinity of the Wuhan University School and Hospital of Stomatology was drawn. Two calibrated examiners orally examined all present grade 2 children in the classroom, using standard caries plaque and tooth morphology criteria. Dental caries was scored at enamel (D2) and dentine (D3) for tooth and surface level. Independent variables were age, gender and school. Data analysis used analysis of variance and t-test. The sample comprised 1 043 7- and 8-year-olds. The prevalence of dental caries in permanent dentition was 8.7% and in primary dentition, 68.7%. Mean Decayed, Missing, Filled Teeth/S (DMFT/S) scores were 0.1 1 and . 14, respectively. Mean dmft/s scores were 2.8 and 5.0. The d-component constituted 75% of the d3mft index, while enamel carious lesions constituted 36% of the total number of carious lesions (d2,3-component). Prevalence of medium and deep pits and fissures was 84.6%. Prevalence of medium and severe plaque accumulation was 67.4%. Prevalence of dental caries in the deciduous and permanent dentitions of 7- to 8-year-old children was high. Deed oits and fissures in high caries risk children should be sealed_
doi_str_mv 10.1038/ijos.2012.34
format Article
fullrecord <record><control><sourceid>wanfang_jour_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3464983</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>43470017</cqvip_id><wanfj_id>gjkqkxzz_e201203007</wanfj_id><sourcerecordid>gjkqkxzz_e201203007</sourcerecordid><originalsourceid>FETCH-LOGICAL-c512t-6d036b69ea897b86c557f016d0b0bae23ef9b8e28d9730bb50605f2287e229ee3</originalsourceid><addsrcrecordid>eNptkc2P0zAQxS0EYsvCjTMy4oLEpoztxLEvSKh8SitxAXG0nMRJ3E3s1k6A7l-Po5ZqQZwszfv5zZsZhJ4SWBNg4rXd-rimQOia5ffQikIuM0a4vI9WhJd5RgURF-hRjFsALgpKHqILSrmUlBcr5N8ZN-kB1zpYE7F2DW5tiBPemTBql0Q8-kEHvLPTSY1xDiZVw673g-8O2DpcZnjyWGQHo0PmhwbXvR2aYNwifp977a7wprdOP0YPWj1E8-T0XqJvH95_3XzKrr98_Lx5e53VBaFTxhtgvOLSaCHLSvC6KMoWSCpXUGlDmWllJQwVjSwZVFUBHIqWUlEaSqUx7BK9Ofru5mo0TZ0GCXpQu2BHHQ7Ka6v-VpztVed_KJbzXAqWDF4dDX5q12rXqa2fg0uRVbe92d_8ur1VZtk6MIAy0S9P7YLfzyZOarSxNsOQVujnqAgIkjMqC5nQF_-gZ2ciACgFSpb2V0eqDj7GYNpzdAJqubta7q6WBClywp_dHfcM_zl0ArIjEJPkOhPudP2_4fNT_967bp--nD1zlpcApGS_AZ6Sw2s</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1800220213</pqid></control><display><type>article</type><title>Dental caries and first permanent molar pit and fissure morphology in 7- to 8-year-old children in Wuhan, China</title><source>Nature Open Access</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Springer Nature OA/Free Journals</source><source>PubMed Central Open Access</source><creator>Wang, Jin-Dong ; Chen, Xi ; Frencken, Jo ; Du, Min-Quan ; Chen, Zhi</creator><creatorcontrib>Wang, Jin-Dong ; Chen, Xi ; Frencken, Jo ; Du, Min-Quan ; Chen, Zhi</creatorcontrib><description>To obtain the caries experience and, plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan, as a reasonable prediction of caries risk and preventive attention in the future, a convenient sample of five primary schools in the vicinity of the Wuhan University School and Hospital of Stomatology was drawn. Two calibrated examiners orally examined all present grade 2 children in the classroom, using standard caries plaque and tooth morphology criteria. Dental caries was scored at enamel (D2) and dentine (D3) for tooth and surface level. Independent variables were age, gender and school. Data analysis used analysis of variance and t-test. The sample comprised 1 043 7- and 8-year-olds. The prevalence of dental caries in permanent dentition was 8.7% and in primary dentition, 68.7%. Mean Decayed, Missing, Filled Teeth/S (DMFT/S) scores were 0.1 1 and . 14, respectively. Mean dmft/s scores were 2.8 and 5.0. The d-component constituted 75% of the d3mft index, while enamel carious lesions constituted 36% of the total number of carious lesions (d2,3-component). Prevalence of medium and deep pits and fissures was 84.6%. Prevalence of medium and severe plaque accumulation was 67.4%. Prevalence of dental caries in the deciduous and permanent dentitions of 7- to 8-year-old children was high. Deed oits and fissures in high caries risk children should be sealed_</description><identifier>ISSN: 1674-2818</identifier><identifier>EISSN: 2049-3169</identifier><identifier>DOI: 10.1038/ijos.2012.34</identifier><identifier>PMID: 22699265</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Child ; China - epidemiology ; Dental Caries - epidemiology ; Dental Caries - prevention &amp; control ; Dental Enamel - pathology ; Dental Fissures - pathology ; Dental Plaque Index ; Dentin - pathology ; Dentistry ; Dentition, Permanent ; DMF Index ; Female ; Humans ; Male ; Medicine ; Molar - pathology ; Oral and Maxillofacial Surgery ; Original ; original-article ; Orthopedics ; Prevalence ; Surgical Orthopedics ; Tooth, Deciduous ; 中国 ; 使用标准 ; 孩子 ; 形态 ; 患病率 ; 武汉市 ; 裂隙 ; 龋齿</subject><ispartof>International journal of oral science, 2012-09, Vol.4 (3), p.157-160</ispartof><rights>The Author(s) 2012</rights><rights>Copyright Nature Publishing Group Sep 2012</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>Copyright © 2012 West China School of Stomatology 2012 West China School of Stomatology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c512t-6d036b69ea897b86c557f016d0b0bae23ef9b8e28d9730bb50605f2287e229ee3</citedby><cites>FETCH-LOGICAL-c512t-6d036b69ea897b86c557f016d0b0bae23ef9b8e28d9730bb50605f2287e229ee3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/89520X/89520X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464983/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464983/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,41096,42165,51551,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22699265$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Jin-Dong</creatorcontrib><creatorcontrib>Chen, Xi</creatorcontrib><creatorcontrib>Frencken, Jo</creatorcontrib><creatorcontrib>Du, Min-Quan</creatorcontrib><creatorcontrib>Chen, Zhi</creatorcontrib><title>Dental caries and first permanent molar pit and fissure morphology in 7- to 8-year-old children in Wuhan, China</title><title>International journal of oral science</title><addtitle>Int J Oral Sci</addtitle><addtitle>International Journal of Oral Science</addtitle><description>To obtain the caries experience and, plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan, as a reasonable prediction of caries risk and preventive attention in the future, a convenient sample of five primary schools in the vicinity of the Wuhan University School and Hospital of Stomatology was drawn. Two calibrated examiners orally examined all present grade 2 children in the classroom, using standard caries plaque and tooth morphology criteria. Dental caries was scored at enamel (D2) and dentine (D3) for tooth and surface level. Independent variables were age, gender and school. Data analysis used analysis of variance and t-test. The sample comprised 1 043 7- and 8-year-olds. The prevalence of dental caries in permanent dentition was 8.7% and in primary dentition, 68.7%. Mean Decayed, Missing, Filled Teeth/S (DMFT/S) scores were 0.1 1 and . 14, respectively. Mean dmft/s scores were 2.8 and 5.0. The d-component constituted 75% of the d3mft index, while enamel carious lesions constituted 36% of the total number of carious lesions (d2,3-component). Prevalence of medium and deep pits and fissures was 84.6%. Prevalence of medium and severe plaque accumulation was 67.4%. Prevalence of dental caries in the deciduous and permanent dentitions of 7- to 8-year-old children was high. Deed oits and fissures in high caries risk children should be sealed_</description><subject>Child</subject><subject>China - epidemiology</subject><subject>Dental Caries - epidemiology</subject><subject>Dental Caries - prevention &amp; control</subject><subject>Dental Enamel - pathology</subject><subject>Dental Fissures - pathology</subject><subject>Dental Plaque Index</subject><subject>Dentin - pathology</subject><subject>Dentistry</subject><subject>Dentition, Permanent</subject><subject>DMF Index</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Molar - pathology</subject><subject>Oral and Maxillofacial Surgery</subject><subject>Original</subject><subject>original-article</subject><subject>Orthopedics</subject><subject>Prevalence</subject><subject>Surgical Orthopedics</subject><subject>Tooth, Deciduous</subject><subject>中国</subject><subject>使用标准</subject><subject>孩子</subject><subject>形态</subject><subject>患病率</subject><subject>武汉市</subject><subject>裂隙</subject><subject>龋齿</subject><issn>1674-2818</issn><issn>2049-3169</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNptkc2P0zAQxS0EYsvCjTMy4oLEpoztxLEvSKh8SitxAXG0nMRJ3E3s1k6A7l-Po5ZqQZwszfv5zZsZhJ4SWBNg4rXd-rimQOia5ffQikIuM0a4vI9WhJd5RgURF-hRjFsALgpKHqILSrmUlBcr5N8ZN-kB1zpYE7F2DW5tiBPemTBql0Q8-kEHvLPTSY1xDiZVw673g-8O2DpcZnjyWGQHo0PmhwbXvR2aYNwifp977a7wprdOP0YPWj1E8-T0XqJvH95_3XzKrr98_Lx5e53VBaFTxhtgvOLSaCHLSvC6KMoWSCpXUGlDmWllJQwVjSwZVFUBHIqWUlEaSqUx7BK9Ofru5mo0TZ0GCXpQu2BHHQ7Ka6v-VpztVed_KJbzXAqWDF4dDX5q12rXqa2fg0uRVbe92d_8ur1VZtk6MIAy0S9P7YLfzyZOarSxNsOQVujnqAgIkjMqC5nQF_-gZ2ciACgFSpb2V0eqDj7GYNpzdAJqubta7q6WBClywp_dHfcM_zl0ArIjEJPkOhPudP2_4fNT_967bp--nD1zlpcApGS_AZ6Sw2s</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Wang, Jin-Dong</creator><creator>Chen, Xi</creator><creator>Frencken, Jo</creator><creator>Du, Min-Quan</creator><creator>Chen, Zhi</creator><general>Nature Publishing Group UK</general><general>Springer Nature B.V</general><general>Shenzhen Maternal and Children's Hospital, Shenzhen, China%Key Laboratory for Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China%Department of Global Oral Health, Radboud University Nijmegen Medical Centre, College of Dental Sciences, Nijmegen, The Netherlands</general><general>Key Laboratory for Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China</general><general>Nature Publishing Group</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope><scope>5PM</scope></search><sort><creationdate>20120901</creationdate><title>Dental caries and first permanent molar pit and fissure morphology in 7- to 8-year-old children in Wuhan, China</title><author>Wang, Jin-Dong ; Chen, Xi ; Frencken, Jo ; Du, Min-Quan ; Chen, Zhi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-6d036b69ea897b86c557f016d0b0bae23ef9b8e28d9730bb50605f2287e229ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Child</topic><topic>China - epidemiology</topic><topic>Dental Caries - epidemiology</topic><topic>Dental Caries - prevention &amp; control</topic><topic>Dental Enamel - pathology</topic><topic>Dental Fissures - pathology</topic><topic>Dental Plaque Index</topic><topic>Dentin - pathology</topic><topic>Dentistry</topic><topic>Dentition, Permanent</topic><topic>DMF Index</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Molar - pathology</topic><topic>Oral and Maxillofacial Surgery</topic><topic>Original</topic><topic>original-article</topic><topic>Orthopedics</topic><topic>Prevalence</topic><topic>Surgical Orthopedics</topic><topic>Tooth, Deciduous</topic><topic>中国</topic><topic>使用标准</topic><topic>孩子</topic><topic>形态</topic><topic>患病率</topic><topic>武汉市</topic><topic>裂隙</topic><topic>龋齿</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Jin-Dong</creatorcontrib><creatorcontrib>Chen, Xi</creatorcontrib><creatorcontrib>Frencken, Jo</creatorcontrib><creatorcontrib>Du, Min-Quan</creatorcontrib><creatorcontrib>Chen, Zhi</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Springer Nature OA/Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of oral science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Jin-Dong</au><au>Chen, Xi</au><au>Frencken, Jo</au><au>Du, Min-Quan</au><au>Chen, Zhi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dental caries and first permanent molar pit and fissure morphology in 7- to 8-year-old children in Wuhan, China</atitle><jtitle>International journal of oral science</jtitle><stitle>Int J Oral Sci</stitle><addtitle>International Journal of Oral Science</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>4</volume><issue>3</issue><spage>157</spage><epage>160</epage><pages>157-160</pages><issn>1674-2818</issn><eissn>2049-3169</eissn><abstract>To obtain the caries experience and, plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan, as a reasonable prediction of caries risk and preventive attention in the future, a convenient sample of five primary schools in the vicinity of the Wuhan University School and Hospital of Stomatology was drawn. Two calibrated examiners orally examined all present grade 2 children in the classroom, using standard caries plaque and tooth morphology criteria. Dental caries was scored at enamel (D2) and dentine (D3) for tooth and surface level. Independent variables were age, gender and school. Data analysis used analysis of variance and t-test. The sample comprised 1 043 7- and 8-year-olds. The prevalence of dental caries in permanent dentition was 8.7% and in primary dentition, 68.7%. Mean Decayed, Missing, Filled Teeth/S (DMFT/S) scores were 0.1 1 and . 14, respectively. Mean dmft/s scores were 2.8 and 5.0. The d-component constituted 75% of the d3mft index, while enamel carious lesions constituted 36% of the total number of carious lesions (d2,3-component). Prevalence of medium and deep pits and fissures was 84.6%. Prevalence of medium and severe plaque accumulation was 67.4%. Prevalence of dental caries in the deciduous and permanent dentitions of 7- to 8-year-old children was high. Deed oits and fissures in high caries risk children should be sealed_</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>22699265</pmid><doi>10.1038/ijos.2012.34</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1674-2818
ispartof International journal of oral science, 2012-09, Vol.4 (3), p.157-160
issn 1674-2818
2049-3169
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3464983
source Nature Open Access; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Springer Nature OA/Free Journals; PubMed Central Open Access
subjects Child
China - epidemiology
Dental Caries - epidemiology
Dental Caries - prevention & control
Dental Enamel - pathology
Dental Fissures - pathology
Dental Plaque Index
Dentin - pathology
Dentistry
Dentition, Permanent
DMF Index
Female
Humans
Male
Medicine
Molar - pathology
Oral and Maxillofacial Surgery
Original
original-article
Orthopedics
Prevalence
Surgical Orthopedics
Tooth, Deciduous
中国
使用标准
孩子
形态
患病率
武汉市
裂隙
龋齿
title Dental caries and first permanent molar pit and fissure morphology in 7- to 8-year-old children in Wuhan, China
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T03%3A21%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wanfang_jour_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dental%20caries%20and%20first%20permanent%20molar%20pit%20and%20fissure%20morphology%20in%207-%20to%208-year-old%20children%20in%20Wuhan,%20China&rft.jtitle=International%20journal%20of%20oral%20science&rft.au=Wang,%20Jin-Dong&rft.date=2012-09-01&rft.volume=4&rft.issue=3&rft.spage=157&rft.epage=160&rft.pages=157-160&rft.issn=1674-2818&rft.eissn=2049-3169&rft_id=info:doi/10.1038/ijos.2012.34&rft_dat=%3Cwanfang_jour_pubme%3Egjkqkxzz_e201203007%3C/wanfang_jour_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1800220213&rft_id=info:pmid/22699265&rft_cqvip_id=43470017&rft_wanfj_id=gjkqkxzz_e201203007&rfr_iscdi=true