1α,25(OH)2-Vitamin D3 Increases Dysferlin Expression in vitro and in a Human Clinical Trial

Dysferlinopathies are a heterogenous group of autosomal recessive inherited muscular dystrophies caused by mutations in DYSF gene. Dysferlin is expressed mainly in skeletal muscle and in monocytes and patients display a severe reduction or absence of protein in both tissues. Vitamin D3 promotes diff...

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Veröffentlicht in:	Molecular therapy 2012-10, Vol.20 (10), p.1988-1997
Hauptverfasser:	Luna, Noemi De, Díaz-Manera, Jordi, Paradas, Carmen, Iturriaga, Cristina, Rojas-García, Ricardo, Araque, Josefa, Genebriera, Mireia, Gich, Ignasi, Illa, Isabel, Gallardo, Eduard
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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