Aurora A kinase expression is increased in leukemia stem cells, and a selective Aurora A kinase inhibitor enhances Ara-C-induced apoptosis in acute myeloid leukemia stem cells

The overexpression of Aurora A kinase (AurA) has been reported in various malignancies, including acute myeloid leukemia (AML). However, the expression of AurA and the effects of AurA inhibition in cancer stem cells are not yet fully understood. We investigated the expression and inhibition of AurA...

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Veröffentlicht in:	Korean journal of hematology 2012-09, Vol.47 (3), p.178-185
Hauptverfasser:	Kim, Soo-Jeong, Jang, Ji Eun, Cheong, June-Won, Eom, Ju-In, Jeung, Hoi-Kyung, Kim, Yundeok, Hwang, Doh Yu, Min, Yoo Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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