Oxygen Consumption and Blood Flow Coupling in Human Motor Cortex during Intense Finger Tapping: Implication for a Role of Lactate

Rates of cerebral blood flow (CBF) and glucose consumption (CMRglc) rise in cerebral cortex during continuous stimulation, while the oxygen-glucose index (OGI) declines as an index of mismatched coupling of oxygen consumption (cerebral metabolic rate of oxygen—CMRO2) to CBF and CMRglc. To test wheth...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2012-10, Vol.32 (10), p.1859-1868
Hauptverfasser:	Vafaee, Manouchehr S, Vang, Kim, Bergersen, Linda H, Gjedde, Albert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apposition Biological and medical sciences Blood Gas Analysis Brain Cerebellum Cerebral blood flow Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cerebrovascular Circulation Cortex Cortex (motor) Energy Metabolism Female Finger Fingers - physiology Fundamental and applied biological sciences. Psychology Glucose Glucose - metabolism Glycolysis Hand Humans Lactic acid Lactic Acid - metabolism Male Medical sciences Metabolic rate Metabolites Motor Activity Motor Cortex - blood supply Motor Cortex - diagnostic imaging Motor Cortex - metabolism Motor task performance Neurology Original Oxygen Consumption Physical training Positron emission tomography supplementary motor area Vascular diseases and vascular malformations of the nervous system Vertebrates: nervous system and sense organs Young Adult
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