The emerging role of mTORC1 signaling in placental nutrient-sensing

Abstract Nutrient-sensing signaling pathways regulate cell metabolism and growth in response to altered nutrient levels and growth factor signaling. Because trophoblast cell metabolism and associated signaling influence fetal nutrient availability, trophoblast nutrient sensors may have a unique role...

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Veröffentlicht in:	Placenta (Eastbourne) 2012-11, Vol.33 (Suppl 2), p.e23-e29
Hauptverfasser:	Jansson, T, Aye, I.L.M.H, Goberdhan, D.C.I
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport Systems Amino acids Amino Acids - metabolism Animals Female Fetal growth Fetal Growth Retardation Fetus Humans Internal Medicine Mammalian target of rapamycin Maternal-Fetal Exchange Mechanistic Target of Rapamycin Complex 1 Multiprotein Complexes - physiology Obstetrics and Gynecology Placenta - physiology Pregnancy Pregnancy Complications Prenatal Nutritional Physiological Phenomena Proton-assisted amino acid transporters Signal Transduction - physiology TOR Serine-Threonine Kinases - physiology Trophoblast Trophoblasts
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