piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism

piRNAs, a class of small non-coding RNAs associated with PIWI proteins, have broad functions in germline development, transposon silencing, and epigenetic regulation. In diverse organisms, a subset of piRNAs derived from repeat sequences are produced via the interplay between two PIWI proteins. This...

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Veröffentlicht in:	Cell research 2012-10, Vol.22 (10), p.1429-1439
Hauptverfasser:	Beyret, Ergin, Liu, Na, Lin, Haifan
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/2434/1822 631/337/384/2054 631/45/173 Animals Argonaute Proteins - genetics Argonaute Proteins - metabolism Biomedical and Life Sciences Cell Biology Cluster Analysis Deoxyribonucleic acid DNA Down-Regulation Genetic Loci Life Sciences Male Meiosis Mice Original original-article Proteins RNA, Small Interfering - chemistry RNA, Small Interfering - metabolism Spermatogenesis Testis - metabolism Up-Regulation 小分子RNA 小鼠睾丸成年小鼠机制生物合成相互作用精子发生蛋白质检测
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