Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

Key points • Several biochemical measures of mitochondrial components are used as biomarkers of mitochondrial content and muscle oxidative capacity. However, no studies have validated these surrogates against a morphological measure of mitochondrial content in human subjects. • The most commonly u...

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Veröffentlicht in:	The Journal of physiology 2012-07, Vol.590 (14), p.3349-3360
Hauptverfasser:	Larsen, Steen, Nielsen, Joachim, Hansen, Christina Neigaard, Nielsen, Lars Bo, Wibrand, Flemming, Stride, Nis, Schroder, Henrik Daa, Boushel, Robert, Helge, Jørn Wulff, Dela, Flemming, Hey‐Mogensen, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - analysis Adult Biomarkers Biomarkers - analysis Cardiolipins - analysis Carrier Proteins - analysis Citrate (si)-Synthase - analysis Electron Transport Complex I - analysis Exercise Test Humans Male Membrane Proteins - analysis Microscopy, Electron, Transmission Mitochondria, Muscle - chemistry Mitochondria, Muscle - ultrastructure Mitochondrial DNA Muscle Fibers, Skeletal - chemistry Muscle Fibers, Skeletal - ultrastructure Musculoskeletal system Oxidative Phosphorylation Oxygen Consumption Quadriceps Muscle - chemistry Quadriceps Muscle - cytology Respiration Skeletal Muscle and Exercise Transmission electron microscopy
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