The efficacy and safety of bevacizumab beyond first progression in patients treated with first-line mFOLFOX6 followed by second-line FOLFIRI in advanced colorectal cancer: a multicenter, single-arm, phase II trial (CCOG-0801)

Purpose The aim of this study was to evaluate the efficacy and safety of the planned continuation of bevacizumab beyond first progression (BBP) in Japanese patients with metastatic colorectal cancer (mCRC). Methods Previously untreated patients with assessable disease were treated with mFOLFOX6 plus...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 2012-10, Vol.70 (4), p.575-581
Hauptverfasser:	Nakayama, Goro, Uehara, Keisuke, Ishigure, Kiyoshi, Yokoyama, Hiroyuki, Ishiyama, Akiharu, Eguchi, Takehiko, Tsuboi, Kenji, Ohashi, Norifumi, Fujii, Tsutomu, Sugimoto, Hiroyuki, Koike, Masahiko, Fujiwara, Michitaka, Ando, Yuich, Kodera, Yasuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - adverse effects Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bevacizumab Biological and medical sciences Camptothecin - analogs & derivatives Camptothecin - therapeutic use Cancer Research Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Disease Progression Female Fluorouracil - therapeutic use Gastroenterology. Liver. Pancreas. Abdomen Humans Leucovorin - therapeutic use Male Medical sciences Medicine Medicine & Public Health Middle Aged Oncology Organoplatinum Compounds - therapeutic use Original Original Article Pharmacology. Drug treatments Pharmacology/Toxicology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
Online-Zugang:	Volltext
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