Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study

Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study

Type 2 diabetes is associated with a marked increase in the risk of coronary artery disease. Dyslipidaemia is believed to be a major cause of this increased risk. Recently, elevated levels of lipoprotein (a), Lp(a), have been reported to be associated with an increased risk. However there is very li...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Indian journal of clinical biochemistry 2002-01, Vol.17 (1), p.45-48
Hauptverfasser: Kumari, S Jaya, Jayaram, Nivedita, Vincent, Lloyd, Venkatesh, T
Format: Artikel
Sprache:eng
Schlagworte:
Cardiovascular disease
Diabetes
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 48
container_issue 1
container_start_page 45
container_title Indian journal of clinical biochemistry
container_volume 17
creator Kumari, S Jaya
Jayaram, Nivedita
Vincent, Lloyd
Venkatesh, T
description Type 2 diabetes is associated with a marked increase in the risk of coronary artery disease. Dyslipidaemia is believed to be a major cause of this increased risk. Recently, elevated levels of lipoprotein (a), Lp(a), have been reported to be associated with an increased risk. However there is very little data regarding Lp(a) concentrations and type 2 diabetes from India. The objective of the study was to assess serum Lp(a) levels in type 2 diabetics with and with out evidence of clinical nephropathy. We estimated serum Lp(a) levels in 30 control subjects, 30 diabetics without evidence of clinical nephropathy and 30 diabetics with evidence of clinical nephropathy. Statistical analysis showed that Lp(a) levels were increased in diabetic patients with nephropathy (mean 46.3±17.6 mg/dl). The Lp(a) levels however did not differ significantly between control (mean 20.2±15.9 mg/dl) and diabetics without nephropathy (mean 22.6±13.1mg/dl). Thus diabetes per se seems to have little or no influence on serum Lp(a) levels, however elevated levels were seen in patients with nephropathy.
doi_str_mv 10.1007/BF02867941
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3453725</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1122632722</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3201-f5dd2dbf7ad1a8e3006401a0b78ea949e02be4a5d7273ca1e4e5d0cd0c4a702f3</originalsourceid><addsrcrecordid>eNpdkUtr3TAQhUVoyKvZ9AcU0VUScDp62LI3gTQkaeBCF223FbI07lWwJVeyE-6_r5tX28DAHJiPwxkOIe8YnDIA9fHTFfC6Uo1kW2QPGiULkJy_edBQsIaVu2Q_51sAIUGyHbLLBYNSiGqP_PiKaR7oajwyx9QH6rxpcfI203s_rakJ7kHEeaJ45x0GizR21PY-eGt6GnBcpziaab0pzumYsPeDDyZtaJ5mt3lLtjvTZzx82gfk-9Xlt4vPxerL9c3F-aqwggMrutI57tpOGcdMjQKgksAMtKpG08gGgbcoTekUV8IahhJLB3YZaRTwThyQs0ffcW4HdBbDlEyvx-SHJYuOxuv_L8Gv9c94p4UsheLlYnD0ZJDirxnzpAefLfa9CRjnrBnjvBJccb6gH16ht3FOYXlPcyWrmlV1tUAnj5BNMeeE3UsWBvpPa_pvawv8_t_0L-hzTeI3hWiS0A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>274681686</pqid></control><display><type>article</type><title>Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study</title><source>SpringerLink Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Kumari, S Jaya ; Jayaram, Nivedita ; Vincent, Lloyd ; Venkatesh, T</creator><creatorcontrib>Kumari, S Jaya ; Jayaram, Nivedita ; Vincent, Lloyd ; Venkatesh, T</creatorcontrib><description>Type 2 diabetes is associated with a marked increase in the risk of coronary artery disease. Dyslipidaemia is believed to be a major cause of this increased risk. Recently, elevated levels of lipoprotein (a), Lp(a), have been reported to be associated with an increased risk. However there is very little data regarding Lp(a) concentrations and type 2 diabetes from India. The objective of the study was to assess serum Lp(a) levels in type 2 diabetics with and with out evidence of clinical nephropathy. We estimated serum Lp(a) levels in 30 control subjects, 30 diabetics without evidence of clinical nephropathy and 30 diabetics with evidence of clinical nephropathy. Statistical analysis showed that Lp(a) levels were increased in diabetic patients with nephropathy (mean 46.3±17.6 mg/dl). The Lp(a) levels however did not differ significantly between control (mean 20.2±15.9 mg/dl) and diabetics without nephropathy (mean 22.6±13.1mg/dl). Thus diabetes per se seems to have little or no influence on serum Lp(a) levels, however elevated levels were seen in patients with nephropathy.</description><identifier>ISSN: 0970-1915</identifier><identifier>EISSN: 0974-0422</identifier><identifier>DOI: 10.1007/BF02867941</identifier><identifier>PMID: 23105336</identifier><language>eng</language><publisher>India: Springer Nature B.V</publisher><subject>Cardiovascular disease ; Diabetes</subject><ispartof>Indian journal of clinical biochemistry, 2002-01, Vol.17 (1), p.45-48</ispartof><rights>Association of Clinical Biochemists of India 2002</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3201-f5dd2dbf7ad1a8e3006401a0b78ea949e02be4a5d7273ca1e4e5d0cd0c4a702f3</citedby><cites>FETCH-LOGICAL-c3201-f5dd2dbf7ad1a8e3006401a0b78ea949e02be4a5d7273ca1e4e5d0cd0c4a702f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3453725/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3453725/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23105336$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumari, S Jaya</creatorcontrib><creatorcontrib>Jayaram, Nivedita</creatorcontrib><creatorcontrib>Vincent, Lloyd</creatorcontrib><creatorcontrib>Venkatesh, T</creatorcontrib><title>Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study</title><title>Indian journal of clinical biochemistry</title><addtitle>Indian J Clin Biochem</addtitle><description>Type 2 diabetes is associated with a marked increase in the risk of coronary artery disease. Dyslipidaemia is believed to be a major cause of this increased risk. Recently, elevated levels of lipoprotein (a), Lp(a), have been reported to be associated with an increased risk. However there is very little data regarding Lp(a) concentrations and type 2 diabetes from India. The objective of the study was to assess serum Lp(a) levels in type 2 diabetics with and with out evidence of clinical nephropathy. We estimated serum Lp(a) levels in 30 control subjects, 30 diabetics without evidence of clinical nephropathy and 30 diabetics with evidence of clinical nephropathy. Statistical analysis showed that Lp(a) levels were increased in diabetic patients with nephropathy (mean 46.3±17.6 mg/dl). The Lp(a) levels however did not differ significantly between control (mean 20.2±15.9 mg/dl) and diabetics without nephropathy (mean 22.6±13.1mg/dl). Thus diabetes per se seems to have little or no influence on serum Lp(a) levels, however elevated levels were seen in patients with nephropathy.</description><subject>Cardiovascular disease</subject><subject>Diabetes</subject><issn>0970-1915</issn><issn>0974-0422</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkUtr3TAQhUVoyKvZ9AcU0VUScDp62LI3gTQkaeBCF223FbI07lWwJVeyE-6_r5tX28DAHJiPwxkOIe8YnDIA9fHTFfC6Uo1kW2QPGiULkJy_edBQsIaVu2Q_51sAIUGyHbLLBYNSiGqP_PiKaR7oajwyx9QH6rxpcfI203s_rakJ7kHEeaJ45x0GizR21PY-eGt6GnBcpziaab0pzumYsPeDDyZtaJ5mt3lLtjvTZzx82gfk-9Xlt4vPxerL9c3F-aqwggMrutI57tpOGcdMjQKgksAMtKpG08gGgbcoTekUV8IahhJLB3YZaRTwThyQs0ffcW4HdBbDlEyvx-SHJYuOxuv_L8Gv9c94p4UsheLlYnD0ZJDirxnzpAefLfa9CRjnrBnjvBJccb6gH16ht3FOYXlPcyWrmlV1tUAnj5BNMeeE3UsWBvpPa_pvawv8_t_0L-hzTeI3hWiS0A</recordid><startdate>200201</startdate><enddate>200201</enddate><creator>Kumari, S Jaya</creator><creator>Jayaram, Nivedita</creator><creator>Vincent, Lloyd</creator><creator>Venkatesh, T</creator><general>Springer Nature B.V</general><general>Springer India</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>04Q</scope><scope>04W</scope><scope>3V.</scope><scope>7XB</scope><scope>88A</scope><scope>88I</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200201</creationdate><title>Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study</title><author>Kumari, S Jaya ; Jayaram, Nivedita ; Vincent, Lloyd ; Venkatesh, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3201-f5dd2dbf7ad1a8e3006401a0b78ea949e02be4a5d7273ca1e4e5d0cd0c4a702f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Cardiovascular disease</topic><topic>Diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumari, S Jaya</creatorcontrib><creatorcontrib>Jayaram, Nivedita</creatorcontrib><creatorcontrib>Vincent, Lloyd</creatorcontrib><creatorcontrib>Venkatesh, T</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>India Database</collection><collection>India Database: Science &amp; Technology</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of clinical biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumari, S Jaya</au><au>Jayaram, Nivedita</au><au>Vincent, Lloyd</au><au>Venkatesh, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study</atitle><jtitle>Indian journal of clinical biochemistry</jtitle><addtitle>Indian J Clin Biochem</addtitle><date>2002-01</date><risdate>2002</risdate><volume>17</volume><issue>1</issue><spage>45</spage><epage>48</epage><pages>45-48</pages><issn>0970-1915</issn><eissn>0974-0422</eissn><abstract>Type 2 diabetes is associated with a marked increase in the risk of coronary artery disease. Dyslipidaemia is believed to be a major cause of this increased risk. Recently, elevated levels of lipoprotein (a), Lp(a), have been reported to be associated with an increased risk. However there is very little data regarding Lp(a) concentrations and type 2 diabetes from India. The objective of the study was to assess serum Lp(a) levels in type 2 diabetics with and with out evidence of clinical nephropathy. We estimated serum Lp(a) levels in 30 control subjects, 30 diabetics without evidence of clinical nephropathy and 30 diabetics with evidence of clinical nephropathy. Statistical analysis showed that Lp(a) levels were increased in diabetic patients with nephropathy (mean 46.3±17.6 mg/dl). The Lp(a) levels however did not differ significantly between control (mean 20.2±15.9 mg/dl) and diabetics without nephropathy (mean 22.6±13.1mg/dl). Thus diabetes per se seems to have little or no influence on serum Lp(a) levels, however elevated levels were seen in patients with nephropathy.</abstract><cop>India</cop><pub>Springer Nature B.V</pub><pmid>23105336</pmid><doi>10.1007/BF02867941</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0970-1915
ispartof Indian journal of clinical biochemistry, 2002-01, Vol.17 (1), p.45-48
issn 0970-1915
0974-0422
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3453725
source SpringerLink Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection
subjects Cardiovascular disease
Diabetes
title Serum Lp(a) in diabetics with and without evidence of clinical nephropathy-A preliminary study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T03%3A21%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Serum%20Lp(a)%20in%20diabetics%20with%20and%20without%20evidence%20of%20clinical%20nephropathy-A%20preliminary%20study&rft.jtitle=Indian%20journal%20of%20clinical%20biochemistry&rft.au=Kumari,%20S%20Jaya&rft.date=2002-01&rft.volume=17&rft.issue=1&rft.spage=45&rft.epage=48&rft.pages=45-48&rft.issn=0970-1915&rft.eissn=0974-0422&rft_id=info:doi/10.1007/BF02867941&rft_dat=%3Cproquest_pubme%3E1122632722%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=274681686&rft_id=info:pmid/23105336&rfr_iscdi=true