Management protocols of Allergic Fungal Sinusitis

Controversy surrounds the appropriate surgical approach and the appropriate medical therapy for Allergic Fungal Sinusitis. The present prospective study aims to assess the impact of these factors on the treatment outcome of Allergic Fungal Sinusitis. In the present study 34 cases with AFS were rando...

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Veröffentlicht in:	Indian Journal of Otolaryngology and Head & Neck Surgery 2007-03, Vol.59 (1), p.35-40
Hauptverfasser:	Gupta, Rishi Pal, Bahadur, Sudhir, Thakar, Alok, Handa, K K, Sarkaar, Chitra
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal agents Aspergillosis Fungal infections Main Otolaryngology Sinusitis
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container_title	Indian Journal of Otolaryngology and Head & Neck Surgery
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creator	Gupta, Rishi Pal Bahadur, Sudhir Thakar, Alok Handa, K K Sarkaar, Chitra
description	Controversy surrounds the appropriate surgical approach and the appropriate medical therapy for Allergic Fungal Sinusitis. The present prospective study aims to assess the impact of these factors on the treatment outcome of Allergic Fungal Sinusitis. In the present study 34 cases with AFS were randomized into one of 3 methods of post operative therapy i.e. systemic itraconazole (group A, n=11), topical steroids (group B, n=12) and nasal alkaline douches only (group C, n=11). Outcome was assessed at 6 months post-operative by the Kupferberg grading system for assessment of nasal and sinus mucosa. Grade '3' mucosal disease was defined as recurrence.Complete pre-operative opacification of sphenoid and frontal sinus was a predictor of poorer outcome. Postoperative systemic itraconazole therapy demonstrated a trend towards a better outcome but was not statistically significant. Larger trials are required to conclusively evaluate the merit of various post-operative treatment regimens for AFS.
doi_str_mv	10.1007/s12070-007-0009-2
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subjects	Antifungal agents Aspergillosis Fungal infections Main Otolaryngology Sinusitis
title	Management protocols of Allergic Fungal Sinusitis
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