Dietary nucleotides increase the mucosal IgA response and the secretion of transforming growth factor β from intestinal epithelial cells in mice

We have investigated the influence of dietary nucleotides on the intestinal immune system in ovalbumin (OVA)-specific T-cell receptor (TCR) transgenic mice (OVA-TCR Tg mice). When mice were supplied with water supplemented with 2% OVA ad libitum, the faecal OVA-specific immunoglobulin A (IgA) level...

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Veröffentlicht in:	Cytotechnology (Dordrecht) 2002-11, Vol.40 (1-3), p.49-58
Hauptverfasser:	NAGAFUCHI, Shinya, TOTSUKA, Mamoru, HACHIMURA, Satoshi, GOTO, Masao, TAKAHASHI, Takeshi, YAJIMA, Takaji, KUWATA, Tamotsu, KAMINOGAWA, Shuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Diet Epithelial cells Fundamental and applied biological sciences. Psychology Growth factors Immune system Immunoglobulin A Interleukin 7 Intestine Lymphocytes T Mucosa Nucleotides Ovalbumin T cell receptors Transforming growth factor-b Transgenic mice
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