Effect of partial medium replacement on cell growth and protein production for the High-Five insect cell line

The potential of spent medium to support the growth and recombinant protein production of High-Five™ cells was investigated. Growth in medium consisting of three parts fresh and one part spent medium was comparable to that in fresh medium (maximal specific growth rates of 0.028 and 0.029 h−1, and ma...

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Veröffentlicht in:Cytotechnology (Dordrecht) 2004, Vol.44 (1-2), p.67-76
Hauptverfasser: IKONOMOU, Laertis, BASTIN, Georges, SCHNEIDER, Yves-Jacques, AGATHOS, Spiros N
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Sprache:eng
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