Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos

The lymphatic vasculature preserves tissue fluid balance by absorbing fluid and macromolecules and transporting them to the blood vessels for circulation. The stepwise process leading to the formation of the mammalian lymphatic vasculature starts by the expression of the gene Prox1 in a subpopulatio...

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Veröffentlicht in:	Blood 2012-09, Vol.120 (11), p.2340-2348
Hauptverfasser:	Yang, Ying, García-Verdugo, José Manuel, Soriano-Navarro, Mario, Srinivasan, R. Sathish, Scallan, Joshua P., Singh, Manvendra K., Epstein, Jonathan A., Oliver, Guillermo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherens Junctions - metabolism Adherens Junctions - ultrastructure Animals Biological and medical sciences Cadherins - metabolism Cell Movement Coronary Vessels - cytology Coronary Vessels - embryology Coronary Vessels - ultrastructure Embryo, Mammalian - blood supply Embryo, Mammalian - cytology Embryo, Mammalian - ultrastructure Embryonic Development Embryonic Stem Cells - cytology Embryonic Stem Cells - ultrastructure Endothelium, Lymphatic - embryology Endothelium, Lymphatic - ultrastructure Hematologic and hematopoietic diseases Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Medical sciences Membrane Glycoproteins - metabolism Mice Mice, Knockout Mice, Transgenic Microscopy, Electron, Transmission Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Recombinant Fusion Proteins - metabolism Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Vascular Biology
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