A Receptor-targeted Fluorescent Radiopharmaceutical for Multireporter Sentinel Lymph Node Imaging

To determine the imaging and receptor-binding properties of a multireporter probe designed for sentinel lymph node (SLN) mapping via nuclear and fluorescence detection. The animal experiments were approved by the institutional animal care and use committee. A multireporter probe was synthesized by c...

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Veröffentlicht in:	Radiology 2012-10, Vol.265 (1), p.186-193
Hauptverfasser:	EMERSON, Derek K, LIMMER, Karl K, HALL, David J, HAN, Sung-Ho, ECKELMAN, William C, KANE, Christopher J, WALLACE, Anne M, VERA, David R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Coloring Agents - chemistry Contrast media. Radiopharmaceuticals Dextrans - chemistry Investigative techniques, diagnostic techniques (general aspects) Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymphatic Metastasis Mannans - chemistry Medical sciences Mice Optical Imaging Organotechnetium Compounds - chemistry Original Research Pentetic Acid - chemistry Pharmacology. Drug treatments Radionuclide Imaging Radiopharmaceuticals - chemistry Sensitivity and Specificity Statistics, Nonparametric Technetium Tc 99m Pentetate - analogs & derivatives
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