How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

The immune system is able to respond more vigorously to the second contact with a given antigen than to the first contact. Vaccination protocols generally include at least two doses, in order to obtain high antibody titers. We want to analyze the relation between the time elapsed from the first dose...

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Veröffentlicht in:Computational and mathematical methods in medicine 2012-01, Vol.2012 (2012), p.1-9
Hauptverfasser: Castiglione, Filippo, Mantile, F., De Berardinis, Piergiuseppe, Prisco, A.
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Sprache:eng
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