Zebrafish rest regulates developmental gene expression but not neurogenesis

The transcriptional repressor Rest (Nrsf) recruits chromatin-modifying complexes to RE1 'silencer elements', which are associated with hundreds of neural genes. However, the requirement for Rest-mediated transcriptional regulation of embryonic development and cell fate is poorly understood...

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Veröffentlicht in:	Development (Cambridge) 2012-10, Vol.139 (20), p.3838-3848
Hauptverfasser:	Kok, Fatma O, Taibi, Andrew, Wanner, Sarah J, Xie, Xiayang, Moravec, Cara E, Love, Crystal E, Prince, Victoria E, Mumm, Jeff S, Sirotkin, Howard I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement Danio rerio Gene Expression Regulation, Developmental Neurogenesis Repressor Proteins - genetics Repressor Proteins - metabolism Transcription, Genetic Zebrafish - embryology Zebrafish - genetics Zebrafish - growth & development Zebrafish - metabolism
Online-Zugang:	Volltext
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