Three-Dimensional Structure and Determinants of Stability of the Iron–Sulfur Cluster Scaffold Protein IscU from Escherichia coli

The highly conserved protein, IscU, serves as the scaffold for iron–sulfur cluster (ISC) assembly in the ISC system common to bacteria and eukaryotic mitochondria. The apo-form of IscU from Escherichia coli has been shown to populate two slowly interconverting conformational states: one structured (...

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Veröffentlicht in:	Biochemistry (Easton) 2012-07, Vol.51 (28), p.5557-5563
Hauptverfasser:	Kim, Jin Hae, Tonelli, Marco, Kim, Taewook, Markley, John L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Apoproteins - chemistry Circular Dichroism Escherichia coli Escherichia coli Proteins - chemistry Iron-Sulfur Proteins - chemistry Models, Molecular Nuclear Magnetic Resonance, Biomolecular Protein Conformation Protein Stability Solutions
Online-Zugang:	Volltext
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