The role of Bicoid cooperative binding in the patterning of sharp borders in Drosophila melanogaster

In Drosophila embryonic development, the Bicoid (Bcd) protein establishes positional information of downstream developmental genes like hunchback (hb), which has a strong anterior expression and a sharp on-off boundary in the mid-embryo. The role of Bcd cooperative binding in the positioning of the...

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Veröffentlicht in:	Developmental biology 2012-10, Vol.370 (2), p.165-172
Hauptverfasser:	Lopes, Francisco J.P, Spirov, Alexander V, Bisch, Paulo M
Format:	Artikel
Sprache:	eng
Schlagworte:	alleles Animals Bicoid Body Patterning Cooperative binding DNA-Binding Proteins - metabolism Drosophila melanogaster Drosophila melanogaster - embryology Drosophila melanogaster - metabolism Drosophila Proteins - metabolism Embryo, Nonmammalian - metabolism embryogenesis Genes, Developmental Hill coefficient Homeodomain Proteins - metabolism Hunchback Self-regulation Trans-Activators - metabolism Transcription Factors - metabolism
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