Increasing local blood flow by warming the application site: beneficial effects on postprandial glycemic excursions

The absorption profile of rapid-acting insulin analogs delivered subcutaneously is slow compared with physiological insulin. Shorter time to peak and shorter duration of insulin action are important steps toward reducing high postprandial blood glucose concentrations in diabetes therapy and are crit...

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Veröffentlicht in:	Journal of diabetes science and technology 2012-07, Vol.6 (4), p.780-785
Hauptverfasser:	Freckmann, Guido, Pleus, Stefan, Haug, Cornelia, Bitton, Gabriel, Nagar, Ron
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Blood Glucose - drug effects Blood Glucose - metabolism Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Hot Temperature - therapeutic use Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - pharmacokinetics Injections, Subcutaneous - instrumentation Injections, Subcutaneous - methods Insulin Infusion Systems Insulin, Short-Acting - administration & dosage Insulin, Short-Acting - pharmacokinetics Models, Biological Postprandial Period - drug effects Regional Blood Flow - physiology Skin - blood supply Skin Absorption - physiology Skin Temperature - physiology Symposium
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