Long read alignment based on maximal exact match seeds

The explosive growth of next-generation sequencing datasets poses a challenge to the mapping of reads to reference genomes in terms of alignment quality and execution speed. With the continuing progress of high-throughput sequencing technologies, read length is constantly increasing and many existin...

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Veröffentlicht in:	Bioinformatics 2012-09, Vol.28 (18), p.i318-i324
Hauptverfasser:	Liu, Yongchao, Schmidt, Bertil
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Chromosome Mapping Genome, Human Genomics - methods High-Throughput Nucleotide Sequencing Humans Original Papers Sequence Alignment - methods Sequence Analysis, DNA - methods Software
Online-Zugang:	Volltext
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