Assessment of dual tasking has no clinical value for fall prediction in Parkinson’s disease
The objective of this study is to investigate the value of dual-task performance for the prediction of falls in patients with Parkinson’s disease (PD). Two hundred sixty-three patients with PD (H&Y 1–3, 65.2 ± 7.9 years) walked two times along a 10-m trajectory, both under single-task and dual-t...
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| Veröffentlicht in: | Journal of neurology 2012-09, Vol.259 (9), p.1840-1847 |
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| container_title | Journal of neurology |
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| creator | Smulders, Katrijn Esselink, Rianne A. J. Weiss, Aner Kessels, Roy P. C. Geurts, Alexander C. H. Bloem, Bastiaan R. |
| description | The objective of this study is to investigate the value of dual-task performance for the prediction of falls in patients with Parkinson’s disease (PD). Two hundred sixty-three patients with PD (H&Y 1–3, 65.2 ± 7.9 years) walked two times along a 10-m trajectory, both under single-task and dual-task (DT) conditions (combined with an auditory Stroop task). To control for a cueing effect, Stroop stimuli were presented at variable or fixed 1- or 2-s intervals. The auditory Stroop task was also performed alone. Dual-task costs were calculated for gait speed, stride length, stride time, stride time variability, step and stride regularity, step symmetry and Stroop composite scores (accuracy/reaction time). Subsequently, falls were registered prospectively for 1 year (monthly assessments). Patients were categorized as non-recurrent fallers (no or 1 fall) or recurrent fallers (>1 falls). Recurrent fallers (35%) had a significantly higher disease severity, lower MMSE scores, and higher Timed “Up & Go” test scores than non-recurrent fallers. Under DT conditions, gait speed and stride lengths were significantly decreased. Stride time, stride time variability, step and stride regularity, and step symmetry did not change under DT conditions. Stroop dual-task costs were only significant for the 2-s Stroop interval trials. Importantly, recurrent fallers did not show different dual-task costs compared to non-recurrent fallers on any of the gait or Stroop parameters. These results did not change after correction for baseline group differences. Deterioration of gait or Stroop performance under dual-task conditions was not associated with prospective falls in this large sample of patients with PD. |
| doi_str_mv | 10.1007/s00415-012-6419-4 |
| format | Article |
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J. ; Weiss, Aner ; Kessels, Roy P. C. ; Geurts, Alexander C. H. ; Bloem, Bastiaan R.</creator><creatorcontrib>Smulders, Katrijn ; Esselink, Rianne A. J. ; Weiss, Aner ; Kessels, Roy P. C. ; Geurts, Alexander C. H. ; Bloem, Bastiaan R.</creatorcontrib><description>The objective of this study is to investigate the value of dual-task performance for the prediction of falls in patients with Parkinson’s disease (PD). Two hundred sixty-three patients with PD (H&Y 1–3, 65.2 ± 7.9 years) walked two times along a 10-m trajectory, both under single-task and dual-task (DT) conditions (combined with an auditory Stroop task). To control for a cueing effect, Stroop stimuli were presented at variable or fixed 1- or 2-s intervals. The auditory Stroop task was also performed alone. Dual-task costs were calculated for gait speed, stride length, stride time, stride time variability, step and stride regularity, step symmetry and Stroop composite scores (accuracy/reaction time). Subsequently, falls were registered prospectively for 1 year (monthly assessments). Patients were categorized as non-recurrent fallers (no or 1 fall) or recurrent fallers (>1 falls). Recurrent fallers (35%) had a significantly higher disease severity, lower MMSE scores, and higher Timed “Up & Go” test scores than non-recurrent fallers. Under DT conditions, gait speed and stride lengths were significantly decreased. Stride time, stride time variability, step and stride regularity, and step symmetry did not change under DT conditions. Stroop dual-task costs were only significant for the 2-s Stroop interval trials. Importantly, recurrent fallers did not show different dual-task costs compared to non-recurrent fallers on any of the gait or Stroop parameters. These results did not change after correction for baseline group differences. Deterioration of gait or Stroop performance under dual-task conditions was not associated with prospective falls in this large sample of patients with PD.</description><identifier>ISSN: 0340-5354</identifier><identifier>EISSN: 1432-1459</identifier><identifier>DOI: 10.1007/s00415-012-6419-4</identifier><identifier>PMID: 22294215</identifier><identifier>CODEN: JNRYA9</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Accidental Falls ; Adult ; Aged ; Analysis of Variance ; Biological and medical sciences ; Clinical trials ; Cognition & reasoning ; Cognition Disorders - diagnosis ; Cognition Disorders - etiology ; Costs ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Education ; Executive function ; Falls ; Female ; Gait ; Gait - physiology ; Humans ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Movement disorders ; Neurodegenerative diseases ; Neurologic Examination ; Neurology ; Neuropsychological Tests ; Neuroradiology ; Neurosciences ; Original Communication ; Parkinson Disease - diagnosis ; Parkinson Disease - physiopathology ; Parkinson's disease ; Performance evaluation ; Psychomotor Performance ; Reaction Time ; Reaction time task ; Task Performance and Analysis ; Walking</subject><ispartof>Journal of neurology, 2012-09, Vol.259 (9), p.1840-1847</ispartof><rights>The Author(s) 2012</rights><rights>2015 INIST-CNRS</rights><rights>Springer-Verlag 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c533t-51ae35a7357333109276b71737765c5d4c58615b6e92f5cc004bf2763d65d6123</citedby><cites>FETCH-LOGICAL-c533t-51ae35a7357333109276b71737765c5d4c58615b6e92f5cc004bf2763d65d6123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00415-012-6419-4$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00415-012-6419-4$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,778,782,883,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26332500$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22294215$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smulders, Katrijn</creatorcontrib><creatorcontrib>Esselink, Rianne A. J.</creatorcontrib><creatorcontrib>Weiss, Aner</creatorcontrib><creatorcontrib>Kessels, Roy P. C.</creatorcontrib><creatorcontrib>Geurts, Alexander C. H.</creatorcontrib><creatorcontrib>Bloem, Bastiaan R.</creatorcontrib><title>Assessment of dual tasking has no clinical value for fall prediction in Parkinson’s disease</title><title>Journal of neurology</title><addtitle>J Neurol</addtitle><addtitle>J Neurol</addtitle><description>The objective of this study is to investigate the value of dual-task performance for the prediction of falls in patients with Parkinson’s disease (PD). Two hundred sixty-three patients with PD (H&Y 1–3, 65.2 ± 7.9 years) walked two times along a 10-m trajectory, both under single-task and dual-task (DT) conditions (combined with an auditory Stroop task). To control for a cueing effect, Stroop stimuli were presented at variable or fixed 1- or 2-s intervals. The auditory Stroop task was also performed alone. Dual-task costs were calculated for gait speed, stride length, stride time, stride time variability, step and stride regularity, step symmetry and Stroop composite scores (accuracy/reaction time). Subsequently, falls were registered prospectively for 1 year (monthly assessments). Patients were categorized as non-recurrent fallers (no or 1 fall) or recurrent fallers (>1 falls). Recurrent fallers (35%) had a significantly higher disease severity, lower MMSE scores, and higher Timed “Up & Go” test scores than non-recurrent fallers. Under DT conditions, gait speed and stride lengths were significantly decreased. Stride time, stride time variability, step and stride regularity, and step symmetry did not change under DT conditions. Stroop dual-task costs were only significant for the 2-s Stroop interval trials. Importantly, recurrent fallers did not show different dual-task costs compared to non-recurrent fallers on any of the gait or Stroop parameters. These results did not change after correction for baseline group differences. Deterioration of gait or Stroop performance under dual-task conditions was not associated with prospective falls in this large sample of patients with PD.</description><subject>Accidental Falls</subject><subject>Adult</subject><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Biological and medical sciences</subject><subject>Clinical trials</subject><subject>Cognition & reasoning</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - etiology</subject><subject>Costs</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Education</subject><subject>Executive function</subject><subject>Falls</subject><subject>Female</subject><subject>Gait</subject><subject>Gait - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Movement disorders</subject><subject>Neurodegenerative diseases</subject><subject>Neurologic Examination</subject><subject>Neurology</subject><subject>Neuropsychological Tests</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Original Communication</subject><subject>Parkinson Disease - diagnosis</subject><subject>Parkinson Disease - physiopathology</subject><subject>Parkinson's disease</subject><subject>Performance evaluation</subject><subject>Psychomotor Performance</subject><subject>Reaction Time</subject><subject>Reaction time task</subject><subject>Task Performance and Analysis</subject><subject>Walking</subject><issn>0340-5354</issn><issn>1432-1459</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkd9qVDEQxoNY7Fp9AG8kIII3p-Z_NjdCKfUPFPRCLyVkc3K2qWeTNXNOwbu-hq_nkzhl11oF8Sow8_sm881HyBPOjjlj9iUwprjuGBedUdx16h5ZcCVFx5V298mCScU6LbU6JA8BLhljS2w8IIdCCKcE1wvy-QQgAWxSmWgdaD-HkU4BvuSyphcBaKk0jrnkiPWrMM6JDrXRIYwj3bbU5zjlWmgu9ENoKIJaflx_B9pnSAHSI3KAKKTH-_eIfHp99vH0bXf-_s2705PzLmopp07zkKQOVmorpeTMCWtWlltprdFR9yrqpeF6ZZITg44Rba8GZGRvdG-4kEfk1W7udl5tUh_RTQuj37a8Ce2bryH7PzslX_h1vfISr2WtwwEv9gNa_TonmPwmQ0zjGEqqM3jOhTBCWrf8P8qM425pmUH02V_oZZ1bwUsgheasNlYjxXdUbBWgpeF2b878Tc5-l7PHnP1Nzl6h5uldw7eKX8Ei8HwPBMDshhZKzPCbM1IKzRhyYscBtso6tbsr_uv3nzypv14</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Smulders, Katrijn</creator><creator>Esselink, Rianne A. 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Prion diseases</topic><topic>Education</topic><topic>Executive function</topic><topic>Falls</topic><topic>Female</topic><topic>Gait</topic><topic>Gait - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Movement disorders</topic><topic>Neurodegenerative diseases</topic><topic>Neurologic Examination</topic><topic>Neurology</topic><topic>Neuropsychological Tests</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Original Communication</topic><topic>Parkinson Disease - diagnosis</topic><topic>Parkinson Disease - physiopathology</topic><topic>Parkinson's disease</topic><topic>Performance evaluation</topic><topic>Psychomotor Performance</topic><topic>Reaction Time</topic><topic>Reaction time task</topic><topic>Task Performance and Analysis</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Smulders, Katrijn</creatorcontrib><creatorcontrib>Esselink, Rianne A. 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J.</au><au>Weiss, Aner</au><au>Kessels, Roy P. C.</au><au>Geurts, Alexander C. H.</au><au>Bloem, Bastiaan R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of dual tasking has no clinical value for fall prediction in Parkinson’s disease</atitle><jtitle>Journal of neurology</jtitle><stitle>J Neurol</stitle><addtitle>J Neurol</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>259</volume><issue>9</issue><spage>1840</spage><epage>1847</epage><pages>1840-1847</pages><issn>0340-5354</issn><eissn>1432-1459</eissn><coden>JNRYA9</coden><abstract>The objective of this study is to investigate the value of dual-task performance for the prediction of falls in patients with Parkinson’s disease (PD). Two hundred sixty-three patients with PD (H&Y 1–3, 65.2 ± 7.9 years) walked two times along a 10-m trajectory, both under single-task and dual-task (DT) conditions (combined with an auditory Stroop task). To control for a cueing effect, Stroop stimuli were presented at variable or fixed 1- or 2-s intervals. The auditory Stroop task was also performed alone. Dual-task costs were calculated for gait speed, stride length, stride time, stride time variability, step and stride regularity, step symmetry and Stroop composite scores (accuracy/reaction time). Subsequently, falls were registered prospectively for 1 year (monthly assessments). Patients were categorized as non-recurrent fallers (no or 1 fall) or recurrent fallers (>1 falls). Recurrent fallers (35%) had a significantly higher disease severity, lower MMSE scores, and higher Timed “Up & Go” test scores than non-recurrent fallers. Under DT conditions, gait speed and stride lengths were significantly decreased. Stride time, stride time variability, step and stride regularity, and step symmetry did not change under DT conditions. Stroop dual-task costs were only significant for the 2-s Stroop interval trials. Importantly, recurrent fallers did not show different dual-task costs compared to non-recurrent fallers on any of the gait or Stroop parameters. These results did not change after correction for baseline group differences. Deterioration of gait or Stroop performance under dual-task conditions was not associated with prospective falls in this large sample of patients with PD.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22294215</pmid><doi>10.1007/s00415-012-6419-4</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Accidental Falls Adult Aged Analysis of Variance Biological and medical sciences Clinical trials Cognition & reasoning Cognition Disorders - diagnosis Cognition Disorders - etiology Costs Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Education Executive function Falls Female Gait Gait - physiology Humans Male Medical sciences Medicine Medicine & Public Health Middle Aged Movement disorders Neurodegenerative diseases Neurologic Examination Neurology Neuropsychological Tests Neuroradiology Neurosciences Original Communication Parkinson Disease - diagnosis Parkinson Disease - physiopathology Parkinson's disease Performance evaluation Psychomotor Performance Reaction Time Reaction time task Task Performance and Analysis Walking |
| title | Assessment of dual tasking has no clinical value for fall prediction in Parkinson’s disease |
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