Tryptophan-based chromophore in fluorescent proteins can be anionic

Cyan fluorescent proteins (CFP) with tryptophan66-based chromophore are widely used for live cell imaging. In contrast to green and red fluorescent proteins, no charged states of the CFP chromophore have been described. Here, we studied synthetic CFP chromophore and found that its indole group can b...

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Veröffentlicht in:	Scientific reports 2012-08, Vol.2 (1), p.608, Article 608
Hauptverfasser:	Sarkisyan, Karen S., Yampolsky, Ilia V., Solntsev, Kyril M., Lukyanov, Sergey A., Lukyanov, Konstantin A., Mishin, Alexander S.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/245 631/45/612 631/61/338 631/92/469 Amino acids Anions Chromophores Green Fluorescent Proteins - chemistry Green Fluorescent Proteins - genetics Humanities and Social Sciences Hydrogen-Ion Concentration Indoles Models, Molecular multidisciplinary Mutagenesis, Site-Directed Protein Conformation Proteins Science Tryptophan Tryptophan - chemistry
Online-Zugang:	Volltext
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