Purine salvage in Leishmania : complex or simple by design?

Purine nucleotides function in a variety of vital cellular and metabolic processes including energy production, cell signaling, synthesis of vitamin-derived cofactors and nucleic acids, and as determinants of cell fate. Unlike their mammalian and insect hosts, Leishmania cannot synthesize the purine...

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Veröffentlicht in:	Trends in parasitology 2012-08, Vol.28 (8), p.345-352
Hauptverfasser:	Boitz, Jan M, Ullman, Buddy, Jardim, Armando, Carter, Nicola S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences drugs energy Gastroenterology and Hepatology General aspects hosts Infectious Disease Infectious diseases insects Leishmania Leishmania - genetics Leishmania - metabolism Leishmania - physiology Leishmaniasis - metabolism Leishmaniasis - parasitology mammals Medical sciences nucleic acids parasites Parasitic diseases parasitology purine nucleotides Purine Nucleotides - metabolism purines
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