Dual roles of Atg8−PE deconjugation by Atg4 in autophagy

Modification of target molecules by ubiquitin or ubiquitin-like (Ubl) proteins is generally reversible. Little is known, however, about the physiological function of the reverse reaction, deconjugation. Atg8 is a unique Ubl protein whose conjugation target is the lipid phosphatidylethanolamine (PE)....

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Veröffentlicht in:	Autophagy 2012-06, Vol.8 (6), p.883-892
Hauptverfasser:	Yu, Zhong-Qiu, Ni, Tao, Hong, Bing, Wang, Hai-Yan, Jiang, Fen-Jun, Zou, Shenshen, Chen, Yong, Zheng, Xi-Long, Klionsky, Daniel J, Liang, Yongheng, Xie, Zhiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Autophagy-Related Protein 8 Family Autophagy-Related Proteins Basic Brief Report Binding Biology Bioscience Calcium Cancer Cell Cycle Intracellular Membranes - metabolism Landes Microtubule-Associated Proteins - metabolism Models, Biological Organogenesis Phagosomes - metabolism Phosphatidylethanolamines - metabolism Proteins Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Vacuoles - metabolism
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