Changes in chromatin structure induced by EDTA treatment and partial removal of histone H1

Electron microscopy shows that EDTA treatment or partial removal of histone HI converts 200–250 Å chromatin fibres characteristic for native chromatin, isolated in low ionic strength conditions into fibres consisting of nucleosomes connected by segments of DNA. This structural transition is accompan...

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Veröffentlicht in:	Nucleic acids research 1977-09, Vol.4 (9), p.3017-3028
Hauptverfasser:	Vengerov, Yu. Yu, Popenko, V. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Chromatin - drug effects Chromatin - ultrastructure Circular Dichroism DNA Edetic Acid Histones Microscopy, Electron Osmolar Concentration Thymus Gland - ultrastructure
Online-Zugang:	Volltext
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