The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

Key Points Podosomes and invadopodia are actin-based dynamic protrusions of the plasma membrane. They act as sites of attachment to — and degradation of — the extracellular matrix. These structures contain actin regulators such as cortactin and neural Wiskott–Aldrich syndrome protein (N-WASP), adapt...

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