Release Factor One Is Nonessential in Escherichia coli

Recoding a stop codon to an amino acid may afford orthogonal genetic systems for biosynthesizing new protein and organism properties. Although reassignment of stop codons has been found in extant organisms, a model organism is lacking to investigate the reassignment process and to direct code evolut...

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Veröffentlicht in:	ACS chemical biology 2012-08, Vol.7 (8), p.1337-1344
Hauptverfasser:	Johnson, David B. F, Wang, Chong, Xu, Jianfeng, Schultz, Matthew D, Schmitz, Robert J, Ecker, Joseph R, Wang, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - chemistry Codon, Terminator Escherichia coli - metabolism Escherichia coli Proteins - metabolism Gene Expression Regulation, Bacterial Genes, Bacterial Genetic Techniques Genomics Green Fluorescent Proteins - metabolism Letters Microscopy, Fluorescence - methods Models, Genetic Mutation Peptide Termination Factors - metabolism Plasmids - metabolism Protein Biosynthesis Time Factors
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