Risk Factors Associated With Secondary Sarcomas in Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study

Purpose Childhood cancer survivors have an increased risk of secondary sarcomas. To better identify those at risk, the relationship between therapeutic dose of chemotherapy and radiation and secondary sarcoma should be quantified. Methods and Materials We conducted a nested case-control study of sec...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2012-09, Vol.84 (1), p.224-230
Hauptverfasser:	Henderson, Tara O., M.D., M.P.H, Rajaraman, Preetha, Ph.D, Stovall, Marilyn, Ph.D, Constine, Louis S., M.D, Olive, Aliza, M.D, Smith, Susan A., M.P.H, Mertens, Ann, Ph.D, Meadows, Anna, M.D, Neglia, Joseph P., M.D., M.P.H, Hammond, Sue, M.D, Whitton, John, M.S, Inskip, Peter D., Sc.D, Robison, Leslie L., Ph.D, Diller, Lisa, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anthracyclines - adverse effects Antibiotics, Antineoplastic - adverse effects Biological and medical sciences Case-Control Studies CHEMOTHERAPY Child Child, Preschool Childhood cancer survivors Confidence Intervals CONTROL DIAGNOSIS Dose-Response Relationship, Radiation Female HEALTH HAZARDS Hematology, Oncology and Palliative Medicine Humans LYMPHOMAS Male MEDICAL RECORDS Medical sciences Middle Aged Neoplasms - drug therapy Neoplasms - radiotherapy Neoplasms, Radiation-Induced - etiology Neoplasms, Second Primary - etiology Odds Ratio RADIATION DOSES Radiation late effects Radiation therapy and radiosensitizing agent Radiology RADIOLOGY AND NUCLEAR MEDICINE Risk Factors Sarcoma - etiology SARCOMAS Secondary sarcomas Survivors Treatment with physical agents Treatment. General aspects Tumors Young Adult
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